Evidence map›Paper›PMID 28500392›Full record

ArticleSurgical case reports2017

A case of advanced gastric cancer achieved a pathological complete response by chemotherapy.

Kazuhiro Tada, Tsuyoshi Etoh, Yuki Shitomi, Yoshitake Ueda, Manabu Tojigamori, Hidefumi Shiroshita, Norio Shiraishi, Masafumi Inomata

Open access · goldAbstract read
In one paragraph

Article in Surgical case reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Kazuhiro TadaDepartment of Gastroenterological and Pediatric Surgery, Oita University Faculty of Medicine, Hasama-machi, Idaigaoka 1-1, Oita, 879-5593, Japan.
Tsuyoshi EtohDepartment of Gastroenterological and Pediatric Surgery, Oita University Faculty of Medicine, Hasama-machi, Idaigaoka 1-1, Oita, 879-5593, Japan. teto@oita-u.ac.jp.
Yuki ShitomiDepartment of Gastroenterological and Pediatric Surgery, Oita University Faculty of Medicine, Hasama-machi, Idaigaoka 1-1, Oita, 879-5593, Japan.
Yoshitake UedaCenter for Community Medicine, Oita University Faculty of Medicine, Oita, Japan.
Manabu TojigamoriDepartment of Gastroenterological and Pediatric Surgery, Oita University Faculty of Medicine, Hasama-machi, Idaigaoka 1-1, Oita, 879-5593, Japan.
Hidefumi ShiroshitaDepartment of Gastroenterological and Pediatric Surgery, Oita University Faculty of Medicine, Hasama-machi, Idaigaoka 1-1, Oita, 879-5593, Japan.
Norio ShiraishiCenter for Community Medicine, Oita University Faculty of Medicine, Oita, Japan.
Masafumi InomataDepartment of Gastroenterological and Pediatric Surgery, Oita University Faculty of Medicine, Hasama-machi, Idaigaoka 1-1, Oita, 879-5593, Japan.
Oita University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlthough chemotherapy is the first recommended treatment of unresectable gastric cancer, a pathological complete response is a rare event. CASE PRESENTATION: A 58-year-old male was diagnosed as gastric cancer with a bulky tumor, lymphadenopathy, and suspicious peritoneal dissemination. The patient underwent chemotherapy with S-1 and cisplatin. After three courses of chemotherapy, a computed tomography showed dramatic improvements in gastric wall thickening, shrinkage of lymphadenopathy, and disappearance of disseminated peritoneal lesion. The patient underwent potentially curative resection by total gastrectomy with D2 lymph node dissection. Histological examination revealed the absence of malignant cells not only in the resected specimen but also in the harvested lymph nodes. At present, more than 7 years after the initial surgery, the patient is still alive without any recurrence.

conclusionsWe obtained a pathological complete response by chemotherapy with S-1 and cisplatin for advanced gastric cancer. Although a pathological complete response is a rare event, it would be associated with the long-term survival of patients with advanced gastric cancer.

Indexed as

Advanced gastric cancerLong-term survivalPathological complete response

Identifiers

PMID28500392
PMCPMC5429316
OpenAlexW2612899243

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.