ArticleScientific reports2017
No evidence of inbreeding depression in a Tasmanian devil insurance population despite significant variation in inbreeding.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- Limited Lifetime Costs of Inbreeding in a Large Wild Population of Superb Fairy-Wrens.Molecular ecology · 2026Article
- Mothers Matter Most: Maternal, but Not Paternal, Age and Inbreeding Affect Nestling Telomere Length in a Wild Passerine.Molecular ecology · 2026Article
- Adaptive potential in the face of a transmissible cancer in Tasmanian devils.Molecular ecology · 2024Article
- Demography and environment modulate the effects of genetic diversity on extinction risk in a butterfly metapopulation.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Genomics reveals introgression and purging of deleterious mutations in the Arabian leopard (iScience · 2023Article
- Whole-genome survey reveals extensive variation in genetic diversity and inbreeding levels among peregrine falcon subspecies.Ecology and evolution · 2023Article
- The relevance of pedigrees in the conservation genomics era.Molecular ecology · 2022Article
- Comparison of genomic diversity and structure of sable antelope (Evolutionary applications · 2020Article
- A comparison of pedigree, genetic and genomic estimates of relatedness for informing pairing decisions in two critically endangered birds: Implications for conservation breeding programmes worldwide.Evolutionary applications · 2020Article
- Inbreeding depression in one of the last DFTD-free wild populations of Tasmanian devils.PeerJ · 2020Article
- Review
- Genomic pedigree reconstruction identifies predictors of mating and reproductive success in an invasive vertebrate.Ecology and evolution · 2019Article
- Conserving adaptive potential: lessons from Tasmanian devils and their transmissible cancer.Conservation genetics (Print) · 2019Article
- Complex problems need detailed solutions: Harnessing multiple data types to inform genetic management in the wild.Evolutionary applications · 2019Article
- The International Mouse Phenotyping Consortium (IMPC): a functional catalogue of the mammalian genome that informs conservation.Conservation genetics (Print) · 2018Article
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Authors and funding
4 authors.
Funding
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Abstract
Inbreeding depression occurs when inbred individuals experience reduced fitness as a result of reduced genome-wide heterozygosity. The Tasmanian devil faces extinction due to a contagious cancer, devil facial tumour disease (DFTD). An insurance metapopulation was established in 2006 to ensure the survival of the species and to be used as a source population for re-wilding and genetic rescue. The emergence of DFTD and the rapid decline of wild devil populations have rendered the species at risk of inbreeding depression. We used 33 microsatellite loci to (1) reconstruct a pedigree for the insurance population and (2) estimate genome-wide heterozygosity for 200 individuals. Using heterozygosity-fitness correlations, we investigated the effect of heterozygosity on six diverse fitness measures (ulna length, asymmetry, weight-at-weaning, testes volume, reproductive success and survival). Despite statistically significant evidence of variation in individual inbreeding in this population, we found no associations between inbreeding and any of our six fitness measurements. We propose that the benign environment in captivity may decrease the intensity of inbreeding depression, relative to the stressful conditions in the wild. Future work will need to measure fitness of released animals to facilitate translation of this data to the broader conservation management of the species in its native range.
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