ArticleScientific reports2017
Catechol-Functional Chitosan/Silver Nanoparticle Composite as a Highly Effective Antibacterial Agent with Species-Specific Mechanisms.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
30 citing papers in PubMed, 128 citations in OpenAlex.
- Radiolytic Synthesis of Chitosan-Stabilized Silver Nanoparticles via Electron Beam Irradiation for Enhanced Antibacterial Activity AgainstInternational journal of molecular sciences · 2026Article
- Design of Poly-Catechol Biodynamers for Potentiation of Antibiotic Efficacy against Drug-Resistant Bacteria.Biomacromolecules · 2026Article
- A Review of Chitosan-Based Electrospun Nanofibers for Food Packaging: From Fabrication to Function and Modeling Insights.Nanomaterials (Basel, Switzerland) · 2025Review
- An Overview of Biopolymer-Based Graphene Nanocomposites for Biotechnological Applications.Materials (Basel, Switzerland) · 2025Review
- Study on Electrochemical Behaviors of Heat-TreatedACS omega · 2024Article
- Effect of Mexican Propolis on Wound Healing in a Murine Model of Diabetes Mellitus.International journal of molecular sciences · 2024Article
- Silver/Graphene Oxide Nanostructured Coatings for Modulating the Microbial Susceptibility of Fixation Devices Used in Knee Surgery.International journal of molecular sciences · 2023Article
- Perspectives on Usage of Functional Nanomaterials in Antimicrobial Therapy for Antibiotic-Resistant Bacterial Infections.ACS omega · 2023Review
- Bactericidal Anti-Adhesion Potential Integrated Polyoxazoline/Silver Nanoparticle Composite Multilayer Film with pH Responsiveness.Polymers · 2022Article
- RETRACTED:Pharmaceutics · 2022Article
- Inactivation of SARS-CoV-2 by a chitosan/α-AgScientific reports · 2022Article
- Antimicrobial activity of chemically and biologically synthesized silver nanoparticles against some fish pathogens.Saudi journal of biological sciences · 2022Article
- Synthesis approach-dependent antiviral properties of silver nanoparticles and nanocomposites.Journal of nanostructure in chemistry · 2022Review
- Antibacterial and corrosion protection properties of SA-CuZnO@ODA-GO composite in circulating cooling water.Environmental science and pollution research international · 2021Article
- Strength, Carbonation Resistance, and Chloride-Ion Penetrability of Cement Mortars Containing Catechol-Functionalized Chitosan Polymer.Materials (Basel, Switzerland) · 2021Article
- Novel light-driven functional AgNPs induce cancer death at extra low concentrations.Scientific reports · 2021Article
- Antibacterial properties of recoverable CuZnO@FeEnvironmental science and pollution research international · 2021Article
- Catechol-Based Antimicrobial Polymers.Molecules (Basel, Switzerland) · 2021Review
- Convenient conversion of hazardous nitrobenzene derivatives to aniline analogues by Ag nanoparticles, stabilized on a naturally magnetic pumice/chitosan substrate.RSC advances · 2020Article
- An Updated Review on Silver Nanoparticles in Biomedicine.Nanomaterials (Basel, Switzerland) · 2020Review
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In this study, silver nanoparticles (Ag NPs) coated with catechol-conjugated chitosan (CSS) were prepared using green methods. Interestingly, we uncovered that CSS-coated Ag NPs (CSS-Ag NPs) exhibited a higher toxicity against gram-negative Escherichia coli (E. coli) bacteria than against gram-positive Staphylococcus aureus (S. aureus) bacteria. The differences revealed that the CSS-Ag NPs killed gram bacteria with distinct, species-specific mechanisms. The aim of this study is to further investigate these underlying mechanisms through a series of analyses. The ultrastructure and morphology of the bacteria before and after treatment with CSS-Ag NPs were observed. The results demonstrated the CSS-Ag NPs killed gram-positive bacteria through a disorganization of the cell wall and leakage of cytoplasmic content. In contrast, the primary mechanism of action on gram-negative bacteria was a change in membrane permeability, induced by adsorption of CSS-Ag NPs. The species-specific mechanisms are caused by structural differences in the cell walls of gram bacteria. Gram-positive bacteria are protected from CSS-Ag NPs by a thicker cell wall, while gram-negatives are more easily killed due to an interaction between a special outer membrane and the nanoparticles. Our study offers an in-depth understanding of the antibacterial behaviors of CSS-Ag NPs and provides insights into ultimately optimizing the design of Ag NPs for treatment of bacterial infections.
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