Evidence map›Paper›PMID 28500292›Full record

ArticleScientific reports2017

Fitness estimates from experimental infections predict the long-term strain structure of a vector-borne pathogen in the field.

Jonas Durand, Maxime Jacquet, Olivier Rais, Lise Gern, Maarten J Voordouw

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.4field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 22 citations in OpenAlex.

  1. Differential Impact of Simultaneous or Sequential Coinfections WithInternational journal of microbiology · 2025
    Article
  2. Adaptive immunity inApplied and environmental microbiology · 2024
    Article
  3. Tick-to-host transmission differs betweenMicrobiology spectrum · 2023
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Ecological and evolutionary perspectives on tick-borne pathogen co-infections.Current research in parasitology & vector-borne diseases · 2021
    Review
  9. Evolutionary ecology of Lyme Borrelia.Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases · 2020
    Review
  10. Review
  11. Article
  12. Article
  13. Competition between strains ofProceedings. Biological sciences · 2018
    Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Jonas DurandLaboratory of Ecology and Evolution of Parasites, Institute of Biology, University of Neuchâtel, Neuchâtel, Switzerland.
Maxime JacquetLaboratory of Ecology and Evolution of Parasites, Institute of Biology, University of Neuchâtel, Neuchâtel, Switzerland.
Olivier RaisLaboratory of Eco-Epidemiology of Parasites, Institute of Biology, University of Neuchâtel, Neuchâtel, Switzerland.
Lise GernLaboratory of Eco-Epidemiology of Parasites, Institute of Biology, University of Neuchâtel, Neuchâtel, Switzerland.
Maarten J VoordouwLaboratory of Ecology and Evolution of Parasites, Institute of Biology, University of Neuchâtel, Neuchâtel, Switzerland. maarten.voordouw@unine.ch.ORCID 0000-0001-9384-0436
University of Neuchâtel · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The populations of many pathogen species consist of a collection of common and rare strains but the factors underlying this strain-specific variation in frequency are often unknown. Understanding frequency variation among strains is particularly challenging for vector-borne pathogens where the strain-specific fitness depends on the performance in both the vertebrate host and the arthropod vector. Two sympatric multiple-strain tick-borne pathogens, Borrelia afzelii and B. garinii, that use the same tick vector, Ixodes ricinus, but different vertebrate hosts were studied. 454-sequencing of the polymorphic ospC gene was used to characterize the community of Borrelia strains in a local population of I. ricinus ticks over a period of 11 years. Estimates of the reproduction number (R

Indexed as

Arthropod VectorsGenetic FitnessAnimalsDisease VectorsPrevalenceTicks

Identifiers

PMID28500292
PMCPMC5431797
OpenAlexW2613269666

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.