Evidence map›Paper›PMID 28500083›Full record

ArticleThe Journal of endocrinology2017

Hepatic thyroid signaling of heat-stressed late pregnant and early lactating cows.

Joachim M Weitzel, Torsten Viergutz, Dirk Albrecht, Rupert Bruckmaier, Marion Schmicke, Armin Tuchscherer, Franziska Koch, Björn Kuhla

Open access · hybridAbstract read
In one paragraph

Article in The Journal of endocrinology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.3field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Joachim M WeitzelInstitute of Reproductive BiologyLeibniz Institute for Farm Animal Biology (FBN), Dummerstorf, Germany.
Torsten ViergutzInstitute of Reproductive BiologyLeibniz Institute for Farm Animal Biology (FBN), Dummerstorf, Germany.
Dirk AlbrechtInstitute of MicrobiologyErnst-Moritz-Arndt-University, Greifswald, Germany.
Rupert BruckmaierVeterinary PhysiologyVetsuisse Faculty, University of Bern, Bern, Switzerland.
Marion SchmickeClinic for CattleEndocrinology Laboratory, University of Veterinary Medicine Hannover, Hannover, Germany.
Armin TuchschererInstitute of Genetics and BiometryLeibniz Institute for Farm Animal Biology (FBN), Dummerstorf, Germany.
Franziska KochInstitute of Nutritional Physiology 'Oskar Kellner'Leibniz Institute for Farm Animal Biology (FBN), Dummerstorf, Germany.
Björn KuhlaInstitute of Nutritional Physiology 'Oskar Kellner'Leibniz Institute for Farm Animal Biology (FBN), Dummerstorf, Germany b.kuhla@fbn-dummerstorf.de.
Research Institute for Farm Animal Biology (FBN) · DEUniversität Greifswald · DEUniversity of Bern · CHUniversity of Veterinary Medicine Hannover, Foundation · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

During the transition between late gestation and early lactation, dairy cows experience severe metabolic stress due to the high energy and nutrient requirements of the fetus and the mammary gland. Additional thermal stress that occurs with rising temperatures during the ongoing climate change has further adverse implications on energy intake, metabolism and welfare. The thyroid hormone (TH)-mediated cellular signaling has a pivotal role in regulation of body temperature, energy intake and metabolic adaptation to heat. To distinguish between energy intake and heat stress-related effects, Holstein cows were first kept at thermoneutrality at 15°C followed by exposure to heat stress (HS) at 28°C or pair-feeding (PF) at 15°C for 6 days, in late pregnancy and again in early lactation. Herein, we focused on hepatic metabolic changes associated with alterations in the hypothalamic-pituitary-thyroid axis in HS and PF animals. T

Indexed as

Pregnancy, AnimalAnimalsBiomarkersCattleCattle DiseasesEnergy MetabolismFemaleHeat Stress DisordersLactationLiverPregnancyRNA, MessengerThyroid GlandThyrotropinThyroxineTriiodothyronineBiomarkersRNA, MessengerThyrotropinThyroxineTriiodothyroninedairy cowheat stressliverthyroid hormone metabolismthyroid-stimulating hormone

Identifiers

PMID28500083
PMCPMC5516449
OpenAlexW2612878056

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.