Evidence map›Paper›PMID 28500049›Full record

ArticleG3 (Bethesda, Md.)2017

Metabolic Adaptation to Nutrients Involves Coregulation of Gene Expression by the RNA Helicase Dbp2 and the Cyc8 Corepressor in

Siwen Wang, Zheng Xing, Pete E Pascuzzi, Elizabeth J Tran

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in G3 (Bethesda, Md.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. The DDX5/Dbp2 subfamily of DEAD-box RNA helicases.Wiley interdisciplinary reviews. RNA · 2019
    Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Siwen WangDepartment of Biochemistry, Purdue University, West Lafayette, Indiana 47907.
Zheng XingDepartment of Biochemistry, Purdue University, West Lafayette, Indiana 47907.
Pete E PascuzziDepartment of Biochemistry, Purdue University, West Lafayette, Indiana 47907 ppascuzz@purdue.edu.
Elizabeth J TranDepartment of Biochemistry, Purdue University, West Lafayette, Indiana 47907 ejtran@purdue.edu.ORCID 0000-0002-9541-004X
Purdue University West Lafayette · USCenter for Cancer Research · US

Funding

Transgenic Mouse Core Facility Shared Resource (TMCF-SR)P30CA023168 · NCI · PURDUE UNIVERSITY WEST LAFAYETTE · PI John Tesmer · 1985 to 2026
$43.4M
The Role of DEAD-box Proteins in Gene ExpressionR01GM097332 · NIGMS · PURDUE UNIVERSITY · PI TRAN, ELIZABETH J · 2011 to 2025
$4.1M
NCI NIH HHS P30 CA023168NIGMS NIH HHS R01 GM097332
6 · The paper itself

Abstract

Cells fine-tune their metabolic programs according to nutrient availability in order to maintain homeostasis. This is achieved largely through integrating signaling pathways and the gene expression program, allowing cells to adapt to nutritional change. Dbp2, a member of the DEAD-box RNA helicase family in

Indexed as

Adaptation, PhysiologicalDEAD-box RNA HelicasesRepressor ProteinsSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsEnergy MetabolismGene DeletionGene Expression Regulation, FungalNuclear ProteinsResponse ElementsCYC8 protein, S cerevisiaeDbp2 protein, S cerevisiaeDEAD-box RNA HelicasesNuclear ProteinsRepressor ProteinsSaccharomyces cerevisiae ProteinsTUP1 protein, S cerevisiaeCyc8Dbp2DEAD-boxhelicasemetabolism

Identifiers

PMID28500049
PMCPMC5499131
OpenAlexW2613229155

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.