ArticleJournal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus2017
Magnetic resonance imaging in dissociated strabismus complex demonstrates generalized hypertrophy of rectus extraocular muscles.
Article in Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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4 citing papers in PubMed, 5 citations in OpenAlex.
- Diffusion tensor imaging of horizontal extraocular muscles in patients with concomitant and paralytic esotropia.International journal of ophthalmology · 2023Article
- Advances in magnetic resonance imaging of orbital disease.Canadian journal of ophthalmology. Journal canadien d'ophtalmologie · 2022Article
- Article
- Involvement of dysregulated coding and long non‑coding RNAs in the pathogenesis of strabismus.Molecular medicine reports · 2018Article
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Authors and funding
3 authors at 2 institutions in 2 countries.
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Abstract
backgroundDissociated strabismus complex (DSC) is an enigmatic form of strabismus that includes dissociated vertical deviation (DVD) and dissociated horizontal deviation (DHD). We employed magnetic resonance imaging (MRI) to evaluate the extraocular muscles in DSC.
methodsWe studied 5 patients with DSC and mean age of 25 years (range, 12-42 years), and 15 age-matched, orthotropic control subjects. All patients had DVD; 4 also had DHD. We employed high-resolution, surface coil MRI with thin, 2 mm slices and central target fixation. Volumes of the rectus and superior oblique muscles in the region 12 mm posterior to 4 mm anterior to the globe-optic nerve junction were measured in quasi-coronal planes in central gaze.
resultsPatients with DSC had no structural abnormalities of rectus muscles or rectus pulleys or the superior oblique muscle but exhibited modest, statistically significant increased volume of all rectus muscles ranging from 20% for medial rectus to 9% for lateral rectus (P < 0.05).
conclusionsDSC includes various combinations of sursumduction, excycloduction, and abduction not conforming to Hering's law. We have found modest generalized enlargement of all rectus muscles. DSC is associated with generalized rectus extraocular muscle hypertrophy in the absence of other orbital abnormalities.
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