Evidence map›Paper›PMID 28499795›Full record

ArticlePhysiology & behavior2017

Anesthesia-inducing drugs also induce conditioned taste aversions.

Jian-You Lin, Joe Arthurs, Steve Reilly

Abstract read
In one paragraph

Article in Physiology & behavior, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jian-You LinUniversity of Illinois at Chicago, United States. Electronic address: jylin@brandeis.edu.
Joe ArthursUniversity of Illinois at Chicago, United States.
Steve ReillyUniversity of Illinois at Chicago, United States. Electronic address: sreilly@uic.edu.

Funding

Parabrachial-Forebrain Interactions in CTAR01DC006456 · NIDCD · UNIVERSITY OF ILLINOIS AT CHICAGO · PI REILLY, STEPHEN · 2004 to 2020
$3.9M
Parabrachial-Forebrain Interactions in Conditioned Taste AversionR56DC006456 · NIDCD · UNIVERSITY OF ILLINOIS AT CHICAGO · PI REILLY, STEPHEN · 2009 to 2009
$339k
NIDCD NIH HHS R01 DC006456NIDCD NIH HHS R56 DC006456
6 · The paper itself

Abstract

Animals learn to reduce their intake of a tastant when its ingestion is followed by the administration of an anesthesia-inducing drug. To determine the nature of this intake suppression, the current study examined whether ketamine/xylazine (Experiment 1) and pentobarbital (Experiment 2) also conditionally reduce taste palatability. Using lick pattern analysis, we found that pairing saccharin with either drug reduced total licks, lick cluster size, and initial lick rate. Given that both lick cluster size and initial lick rate are indices of palatability, this pattern of results indicates that anesthesia-inducing drugs also induce conditioned taste aversions.

Indexed as

AnestheticsAnimalsAvoidance LearningConditioning, PsychologicalFood PreferencesKetamineMaleMotor ActivityPentobarbitalPsychotropic DrugsRats, Sprague-DawleyTongueXylazineAnestheticsKetaminePentobarbitalPsychotropic DrugsXylazineAversion-avoidanceKetamine/xylazinePentobarbitalRatTaste palatability

Identifiers

PMID28499795
PMCPMC5857295

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.