Evidence map›Paper›PMID 28499500›Full record

ReviewTrends in biochemical sciences2017

Ca

Ran Zalk, Andrew R Marks

Open access · greenAbstract readReview
In one paragraph

Review in Trends in biochemical sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 45 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. The Concise Guide to PHARMACOLOGY 2023/24: Ion channels.British journal of pharmacology · 2023
    Article
  5. Article
  6. Article
  7. Targeting ryanodine receptors to treat human diseases.The Journal of clinical investigation · 2023
    Review
  8. Review
  9. Article
  10. Article
  11. iASPP suppresses Gp78-mediated TMCO1 degradation to maintain CaProceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  12. Article
  13. Regulatory mechanisms of ryanodine receptor/CaJournal of muscle research and cell motility · 2021
    Review
  14. Calmodulin Mutations Associated with Heart Arrhythmia: A Status Report.International journal of molecular sciences · 2020
    Review
  15. Article
  16. Article
  17. Article
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Ran ZalkThe National Institute for Biotechnology in the Negev, Ben-Gurion University of the Negev, Beer Sheva 84105, Israel.
Andrew R MarksDepartment of Physiology and Cellular Biophysics, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA; Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA; Wu Center for Molecular Cardiology, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA. Electronic address: arm42@cumc.columbia.edu.
Ben-Gurion University of the Negev · ILColumbia University · US

Funding

Molecular Basis of Sudden Cardiac DeathP01HL067849 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI D'ARMIENTO, JEANINE M · 2001 to 2011
$15.0M
MOLECULAR BASIS OF HEART FAILURER01HL061503 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MARKS, ANDREW ROBERT · 1998 to 2016
$6.5M
(PQ#9)Targeting leaky ryanodine receptor (RyR2) to treat and prevent chemotherapy-associated cognitive dysfunction in patients with breast cancer.R01CA206025 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI GUISE, THERESA A, MARKS, ANDREW ROBERT · 2016 to 2020
$3.2M
Intracellular calcium leak and muscle functionR01AR060037 · NIAMS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MARKS, ANDREW ROBERT · 2010 to 2014
$1.7M
NCI NIH HHS R01 CA206025NHLBI NIH HHS P01 HL067849NHLBI NIH HHS R01 HL061503NIAMS NIH HHS R01 AR060037
6 · The paper itself

Abstract

Ryanodine receptors (RyRs) are calcium release channels expressed in the sarcoendoplasmic reticula of many cell types including cardiac and skeletal muscle cells. In recent years Ca

Indexed as

AnimalsCalciumHumansModels, MolecularRyanodine Receptor Calcium Release ChannelCalciumRyanodine Receptor Calcium Release Channelcalcium channelcryo-EMexcitation–contraction couplingryanodine receptorsstructure

Identifiers

PMID28499500
PMCPMC5875148
OpenAlexW2612848250

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.