Evidence map›Paper›PMID 28499440›Full record

Trial reportTrials2017

A feasibility randomised controlled trial of extended brief intervention for alcohol misuse in adults with mild to moderate intellectual disabilities living in the community; The EBI-LD study.

Christos Kouimtsidis, Alessandro Bosco, Katrina Scior, Gianluca Baio, Rachael Hunter, Vittoria Pezzoni, Eileen Mcnamara, Angela Hassiotis

Open access · goldAbstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Trials, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 2 pooled it
5.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 2 syntheses or guidelines pooled it, 32 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Christos KouimtsidisiHEAR, Surrey and Borders Partnership NHS Foundation Trust, 1 Prince Regent Road, London, TW3 1NE, UK. drckouimtsidis@hotmail.com.ORCID 0000-0001-9975-2955
Alessandro BoscoDivision of Psychiatry, University College London, Maple House, 149 Tottenham Court Road, W1T 7NF, London, UK.
Katrina SciorResearch Department of Clinical, Educational and Health Psychology, University College London, 1-19 Torrington Place, WC1E 6BT, London, UK.
Gianluca BaioDepartment of Statistical Science, University College London, 1-19 Torrington Place, London, WC1E 6BT, UK.
Rachael HunterDepartment of Primary Care and Population Health Research, University College London, Royal Free Hospital Rowland Hill Street, NW3 2PF, London, UK.
Vittoria PezzoniHertfordshire Partnership NHS Foundation Trust, Woodside Road, Abbots Langley, Watford, WD5 0HT, UK.
Eileen McnamaraBarnet, Enfield and Haringey Mental Health NHS Trust, Barnet House 1255 High Road, London, N20 0EJ, UK.
Angela HassiotisDivision of Psychiatry, University College London, Maple House, 149 Tottenham Court Road, W1T 7NF, London, UK.
University College London · GBBarnet Enfield and Haringey Mental Health Trust · GBHertfordshire Partnership University NHS Foundation Trust · GBSurrey and Borders Partnership NHS Foundation Trust · GBThe Royal Free Hospital · GB

Funding

Department of Health PB-PG-1111-26022
6 · The paper itself

Abstract

backgroundExtended brief interventions (EBIs) are effective in targeting alcohol misuse in the general population. However, little is known of the effects of EBI in adults with intellectual (also known as learning) disabilities. In this feasibility trial we compared EBI with usual care for alcohol misuse in adults with mild to moderate Intellectual Disability (ID).

methodsThe study took place in three community ID networks of services in England. Participants aged 18-65 years with reported alcohol problems, a score ≥8 on the Alcohol Use Disorder Identification Test (AUDIT), and IQ <70 (+/5%CI) were recruited and were randomly allocated to either EBI (five weekly sessions and one follow-up at 8 weeks) and usual care or usual care alone. Research assistants were blind to arm allocation. Research assessments took place at baseline, 2 and 3 months. The primary outcome was reduction in alcohol consumption measured by the AUDIT. Preliminary health economic analysis was performed to investigate the costs of delivering EBI and the feasibility of a cost-effectiveness analysis in a full trial. The trial is closed.

resultsParticipants were recruited from January 2014 to August 2015. Thirty individuals were randomised (15 in each arm) and provided primary outcome data. In regard to harmful drinking, at baseline, all the participants exceeded the relevant threshold. At 8 weeks, the proportion of participants with harmful drinking had decreased to 60% for both groups, and at 12 weeks it had decreased by 66°7% and 46°7% for the intervention and the control groups, respectively. The unit cost for the delivery of EBI is £430.

conclusionsRecruitment to this trial has been proven challenging as prevalence of alcohol misuse in the targeted population was lower than anticipated. EBI may provide an effective low-intensity treatment for this population. Participants' and carers' feedback on their experience was overall positive. Further work needs to be undertaken to ascertain the group of participants that should be participating in a future definitive trial.

trial registrationPsychological Intervention Alcohol Misuse Learning Disability; isrctn.com, identifier: ISRCTN58783633 . Registered on 17 December 2013.

Indexed as

Independent LivingAdultAgedAlcohol DrinkingAlcohol-Related DisordersCost-Benefit AnalysisEnglandFeasibility StudiesFemaleHealth Care CostsHumansIntellectual DisabilityMaleMiddle AgedPatient SelectionPersons with Intellectual DisabilitiesAlcohol misuseBrief interventionIntellectual disabilities

Identifiers

PMID28499440
PMCPMC5427589
OpenAlexW2612389952

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.