Evidence map›Paper›PMID 28499289›Full record

ArticleSexually transmitted diseases2017

Maternal Syphilis: An Independent Risk Factor for Mother to Infant Human Immunodeficiency Virus Transmission.

Aarti Kinikar, Nikhil Gupte, Jayalakshmi Bhat, Renu Bharadwaj, Vandana Kulkarni, Ramesh Bhosale, Katherine N McIntire, Vidya Mave, Nishi Suryavanshi, Sandesh Patil and 2 more

Open access · hybridAbstract read
In one paragraph

Article in Sexually transmitted diseases, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 2 countries.

Aarti KinikarFrom the *Byramjee Jeejeebhoy Government Medical College and Sassoon General Hospital, Pune, Maharashtra, India; †Division of Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, MD; ‡Byramjee Jeejeebhoy Government Medical College-Johns Hopkins University Clinical Research Site, Pune, Maharashtra, India; and §International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD.
Nikhil Gupte
Jayalakshmi Bhat
Renu Bharadwaj
Vandana Kulkarni
Ramesh Bhosale
Katherine N McIntire
Vidya Mave
Nishi Suryavanshi
Sandesh Patil
Robert Bollinger
Amita Gupta
Johns Hopkins University · USB. J. Medical College & Sassoon Hospital · INJohns Hopkins Medicine · US

Funding

The Johns Hopkins Baltimore-Washington-India Clinical Trials Unit (BWI CTU)UM1AI069465 · NIAID · JOHNS HOPKINS UNIVERSITY · PI Charles W. Flexner, Amita Gupta · 2012 to 2026
$34.1M
TUBERCULOSIS INTERNATIONAL TRAINING AND RESEARCH PROGRAMD43TW000010 · FIC · JOHNS HOPKINS UNIVERSITY · PI BEYRER, CHRISTOPHER C. · 1988 to 2012
$19.8M
PREVENTION MATERNAL TO INFANT HIV TRANSMISSION IN INDIAR01AI045462 · NIAID · JOHNS HOPKINS UNIVERSITY · PI BOLLINGER, ROBERT C · 1999 to 2005
$5.8M
Byramee Jeejeebhoy Medical College (BJMC), Pune, India: Clinical Trials UnitU01AI069497 · NIAID · JOHNS HOPKINS UNIVERSITY · PI GUPTA, AMITA · 2007 to 2011
$4.1M
HIV-TB Fogarty Research Training ProgramD43TW009574 · FIC · JOHNS HOPKINS UNIVERSITY · PI BOLLINGER, ROBERT C. · 2013 to 2017
$1.0M
FIC NIH HHS D43 TW000010FIC NIH HHS D43 TW009574NIAID NIH HHS R01 AI045462NIAID NIH HHS U01 AI069497NIAID NIH HHS UM1 AI069465
6 · The paper itself

Abstract

Syphilis is associated with increased human immunodeficiency virus acquisition and sexual transmission; we examined impact on human immunodeficiency virus mother-to-child transmission among mother-infant pairs enrolled in the India Six-Week Extended-Dose Nevirapine study. Maternal syphilis, diagnosed serologically using Venereal Disease Research Laboratory titer plus Treponema Pallidum Hemagglutination Assay, was associated with 2.5-fold greater risk.

Indexed as

Point-of-Care TestingSyphilis SerodiagnosisAdultAnti-HIV AgentsCD4 Lymphocyte CountClinical Trials, Phase III as TopicCost-Benefit AnalysisFemaleFollow-Up StudiesHIV-1HIV InfectionsHumansIndiaInfant, NewbornInfectious Disease Transmission, VerticalMaleAnti-HIV AgentsNevirapine

Identifiers

PMID28499289
PMCPMC5434955
OpenAlexW2604240555

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.