Evidence map›Paper›PMID 28499087›Full record

ArticleJournal of the American Chemical Society2017

Identification of Intrahelical Bifurcated H-Bonds as a New Type of Gate in K

Oliver Rauh, Martin Urban, Leonhard M Henkes, Tobias Winterstein, Timo Greiner, James L Van Etten, Anna Moroni, Stefan M Kast, Gerhard Thiel, Indra Schroeder

Open access · bronzeAbstract read
In one paragraph

Article in Journal of the American Chemical Society, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 21 citations in OpenAlex.

  1. Similarity of the ion occupations of KChannels (Austin, Tex.) · 2026
    Article
  2. Modular architecture of KEMBO reports · 2025
    Review
  3. Article
  4. Article
  5. Article
  6. Asymmetric Interplay Between KFrontiers in physiology · 2021
    Article
  7. A Functional KViruses · 2020
    Article
  8. Quantitative Analysis of Multiplex H-Bonds.Journal of the American Chemical Society · 2020
    Article
  9. Article
  10. Article
  11. Review
  12. Coupling of a viral KCommunications biology · 2019
    Article
  13. Article
  14. Exploring the Viral Channel KcvThe Journal of membrane biology · 2018
    Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 3 countries.

Oliver RauhPlant Membrane Biophysics, Technical University Darmstadt , 64289 Darmstadt, Germany.
Martin UrbanPhysikalische Chemie III, Technische Universität Dortmund , 44227 Dortmund, Germany.
Leonhard M HenkesPhysikalische Chemie III, Technische Universität Dortmund , 44227 Dortmund, Germany.
Tobias WintersteinPlant Membrane Biophysics, Technical University Darmstadt , 64289 Darmstadt, Germany.
Timo GreinerPlant Membrane Biophysics, Technical University Darmstadt , 64289 Darmstadt, Germany.
James L Van EttenDepartment of Plant Pathology and Nebraska Center for Virology, University of Nebraska Lincoln , Lincoln, Nebraska 68583-0900, United States.
Anna MoroniDepartment of Biosciences and CNR IBF-Mi, Università degli Studi di Milano , 20122 Milano, Italy.
Stefan M KastPhysikalische Chemie III, Technische Universität Dortmund , 44227 Dortmund, Germany.ORCID 0000-0001-7346-7064
Gerhard ThielPlant Membrane Biophysics, Technical University Darmstadt , 64289 Darmstadt, Germany.ORCID 0000-0002-2335-1351
Indra SchroederPlant Membrane Biophysics, Technical University Darmstadt , 64289 Darmstadt, Germany.
Technische Universität Darmstadt · DETU Dortmund University · DEUniversity of Milan · ITUniversity of Nebraska–Lincoln · US

Funding

Nebraska Center for VirologyP30GM103509 · NIGMS · UNIVERSITY OF NEBRASKA LINCOLN · PI WOOD, CHARLES · 2012 to 2014
$3.3M
Mentored Patient-Oriented Research Career Development AwK23RR015535 · NCRR · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI AFONJA, OLUBUMMI OLUTOYIN · 2000 to 2004
$657k
European Research Council 695078NCRR NIH HHS K23 RR015535NIGMS NIH HHS P30 GM103509
6 · The paper itself

Abstract

Gating of ion channels is based on structural transitions between open and closed states. To uncover the chemical basis of individual gates, we performed a comparative experimental and computational analysis between two K

Indexed as

Ion Channel GatingMolecular Dynamics SimulationAmino Acid SequenceHydrogen BondingModels, MolecularPotassium ChannelsSequence AlignmentPotassium Channels

Identifiers

PMID28499087
PMCPMC6638992
OpenAlexW2612939138

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.