Evidence map›Paper›PMID 28498638›Full record

ArticleAngewandte Chemie (International ed. in English)2017

Assessing the Influence of Mutation on GTPase Transition States by Using X-ray Crystallography,

Yi Jin, Robert W Molt, Erika Pellegrini, Matthew J Cliff, Matthew W Bowler, Nigel G J Richards, G Michael Blackburn, Jonathan P Waltho

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 4 countries.

Yi JinDepartment of Molecular Biology and Biotechnology, Krebs Institute, University of Sheffield, Sheffield, S10 2TN, UK.ORCID 0000-0002-6927-4371
Robert W MoltSchool of Chemistry, Cardiff University, Cardiff, CF10 3AT, UK.
Erika PellegriniStructural Biology Group, ESRF-The European Synchrotron, CS40220, 38043, Grenoble, Cedex 9, France.
Matthew J CliffManchester Institute of Biotechnology, Manchester, M1 7DN, UK.
Matthew W BowlerStructural Biology Group, ESRF-The European Synchrotron, CS40220, 38043, Grenoble, Cedex 9, France.
Nigel G J RichardsSchool of Chemistry, Cardiff University, Cardiff, CF10 3AT, UK.
G Michael BlackburnDepartment of Molecular Biology and Biotechnology, Krebs Institute, University of Sheffield, Sheffield, S10 2TN, UK.
Jonathan P WalthoDepartment of Molecular Biology and Biotechnology, Krebs Institute, University of Sheffield, Sheffield, S10 2TN, UK.
Cardiff University · GBEuropean Synchrotron Radiation Facility · FRUniversity of Manchester · GBEnsco (United States) · USUniversity of Sheffield · GB

Funding

Biotechnology and Biological Sciences Research Council BB/E017541/1
6 · The paper itself

Abstract

We report X-ray crystallographic and

Indexed as

Density Functional TheoryCrystallography, X-RayFluorineGTP PhosphohydrolasesMagnetic Resonance SpectroscopyModels, MolecularMutationFluorineGTP Phosphohydrolases19F NMRDFT calculationsenzyme mechanismsGTPasesRhoA/RhoGAP

Identifiers

PMID28498638
PMCPMC5575484
OpenAlexW2613300067

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.