Evidence map›Paper›PMID 28498310›Full record

ArticleInternational journal of molecular sciences2017

Selective Expression of Flt3 within the Mouse Hematopoietic Stem Cell Compartment.

Ciaran James Mooney, Alan Cunningham, Panagiotis Tsapogas, Kai-Michael Toellner, Geoffrey Brown

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 45 citations in OpenAlex.

  1. Article
  2. Review
  3. Cell Lineage Affiliation During Hematopoiesis.International journal of molecular sciences · 2025
    Review
  4. Review
  5. HES1 is required for mouse fetal hematopoiesis.Stem cell research & therapy · 2024
    Article
  6. Review
  7. Review
  8. Review
  9. Flt3 Signaling in B Lymphocyte Development and Humoral Immunity.International journal of molecular sciences · 2022
    Review
  10. The Social Norm of Hematopoietic Stem Cells and Dysregulation in Leukemia.International journal of molecular sciences · 2022
    Review
  11. Article
  12. Oncogenes and the Origins of Leukemias.International journal of molecular sciences · 2022
    Review
  13. Article
  14. Lessons to cancer from studies of leukemia and hematopoiesis.Frontiers in cell and developmental biology · 2022
    Review
  15. OralFrontiers in cellular and infection microbiology · 2022
    Article
  16. Oncogenes, Proto-Oncogenes, and Lineage Restriction of Cancer Stem Cells.International journal of molecular sciences · 2021
    Review
  17. Hematopoietic Stem Cells: Nature and Niche Nurture.Bioengineering (Basel, Switzerland) · 2021
    Review
  18. Article
  19. Article
  20. Towards a New Understanding of Decision-Making by Hematopoietic Stem Cells.International journal of molecular sciences · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Ciaran James MooneyInstitute of Immunology and Immunotherapy, College of Medical and Dental Sciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK. c.mooney@smd15.qmul.ac.uk.
Alan CunninghamInstitute of Immunology and Immunotherapy, College of Medical and Dental Sciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK. alan.cunningham43@gmail.com.
Panagiotis TsapogasDevelopmental and Molecular Immunology, Department of Biomedicine, University of Basel, Basel 4058, Switzerland. panagiotis.tsapogas@unibas.ch.
Kai-Michael ToellnerInstitute of Immunology and Immunotherapy, College of Medical and Dental Sciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK. k.m.toellner@bham.ac.uk.
Geoffrey BrownInstitute of Immunology and Immunotherapy, College of Medical and Dental Sciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK. g.brown@bham.ac.uk.
University of Birmingham · GBUniversity of Basel · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The fms-like tyrosine kinase 3 (Flt3) is a cell surface receptor that is expressed by various hematopoietic progenitor cells (HPC) and Flt3-activating mutations are commonly present in acute myeloid and lymphoid leukemias. These findings underscore the importance of Flt3 to steady-state and malignant hematopoiesis. In this study, the expression of Flt3 protein and

Indexed as

Animalsfms-Like Tyrosine Kinase 3HematopoiesisHematopoietic Stem CellsMaleMiceMice, Inbred C57BLReceptor, Macrophage Colony-Stimulating FactorReceptors, ErythropoietinRNA, MessengerFlt3 protein, mousefms-Like Tyrosine Kinase 3Receptor, Macrophage Colony-Stimulating FactorReceptors, ErythropoietinRNA, MessengercytokinesFlt3growth factor receptorshematopoiesisHSCleukemia

Identifiers

PMID28498310
PMCPMC5454949
OpenAlexW2612256351

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.