Evidence map›Paper›PMID 28497915›Full record

ReviewAllergy, asthma & immunology research2017

In Vitro Diagnostic Testing for Antibiotic Allergy.

Inmaculada Doña, Maria J Torres, Maria I Montañez, Tahia D Fernández

Abstract readReview
In one paragraph

Review in Allergy, asthma & immunology research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. A new pathway for penicillin delabeling in Norway.The World Allergy Organization journal · 2023
    Article
  6. Review
  7. Review
  8. Review
  9. Development and initial validation of a modified lymphocyte transformation test (LTT) assay in patients with DRESS and AGEP.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2022
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Frontiers in immunology · 2021
    Review
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Inmaculada DoñaAllergy Unit, IBIMA-Regional University Hospital of Malaga-UMA, Málaga, Spain.
Maria J TorresAllergy Unit, IBIMA-Regional University Hospital of Malaga-UMA, Málaga, Spain. mjtorresj@ibima.eu.
Maria I MontañezAndalusian Center for Nanomedicine and Biotechnology-BIONAND, Málaga, Spain.
Tahia D FernándezResearch Laboratory, IBIMA-Regional University Hospital of Malaga-UMA, Málaga, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Allergy to antibiotics is an important worldwide problem, with an estimated prevalence of up to 10% of the population. Reaction patterns for different antibiotics have changed in accordance with consumption trends. Most of the allergic reactions to antibiotics have been reported for betalactams, followed by quinolones and macrolides and, to a lesser extent, to others, such as metronidazole clindamycin and sulfonamides. The diagnostic procedure includes a detailed clinical history, which is not always possible and can be unreliable. This is usually followed by in vivo, skin, and drug provocation tests. These are not recommended for severe, potentially lifethreaten reactions or for drugs that are known to produce a high rate of false positive results. Given the limitations of in vivo tests, in vitro test can be helpful for diagnosis, despite having suboptimal sensitivity. The most highly employed techniques for diagnosing immediate reactions to antibiotics are immunoassays and basophil activation tests, while lymphocyte transformation tests are more commonly used to diagnose non-immediate reactions. In this review, we describe different in vitro techniques employed to diagnose antibiotic allergy.

Indexed as

Antibioticdrug allergyin vitro test

Identifiers

PMID28497915
PMCPMC5446943

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.