Evidence map›Paper›PMID 28497789›Full record

ArticleNature communications2017

Underwater Leidenfrost nanochemistry for creation of size-tailored zinc peroxide cancer nanotherapeutics.

Mady Elbahri, Ramzy Abdelaziz, Duygu Disci-Zayed, Shahin Homaeigohar, Justyna Sosna, Dieter Adam, Lorenz Kienle, Torben Dankwort, Moheb Abdelaziz

Abstract read
In one paragraph

Article in Nature communications, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Non-Equilibrium Synthesis Methods to Create Metastable and High-Entropy Nanomaterials.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
  5. pH-triggered CS@ZnOFrontiers in bioengineering and biotechnology · 2025
    Article
  6. Article
  7. Review
  8. Article
  9. Metal peroxides for cancer treatment.Bioactive materials · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Mady ElbahriNanochemistry and Nanoengineering, School of Chemical Engineering, Department of Chemistry and Materials Science, Aalto University, Kemistintie 1, 00076 Aalto, Finland.
Ramzy AbdelazizNanochemistry and Nanoengineering, School of Chemical Engineering, Department of Chemistry and Materials Science, Aalto University, Kemistintie 1, 00076 Aalto, Finland.
Duygu Disci-ZayedNanochemistry and Nanoengineering, Institute for Materials Science, Faculty of Engineering, Kiel University, Kaiserstrasse 2, 24143 Kiel, Germany.
Shahin HomaeigoharNanochemistry and Nanoengineering, School of Chemical Engineering, Department of Chemistry and Materials Science, Aalto University, Kemistintie 1, 00076 Aalto, Finland.
Justyna SosnaInstitute of Immunology, Kiel University, Michaelisstrasse 5, 24105 Kiel, Germany.
Dieter AdamInstitute of Immunology, Kiel University, Michaelisstrasse 5, 24105 Kiel, Germany.ORCID 0000-0002-5668-5032
Lorenz KienleSynthesis and Real Structure, Institute for Materials Science, Faculty of Engineering, Kiel University, Kaiserstrasse 2, 24143 Kiel, Germany.
Torben DankwortSynthesis and Real Structure, Institute for Materials Science, Faculty of Engineering, Kiel University, Kaiserstrasse 2, 24143 Kiel, Germany.
Moheb AbdelazizNanochemistry and Nanoengineering, School of Chemical Engineering, Department of Chemistry and Materials Science, Aalto University, Kemistintie 1, 00076 Aalto, Finland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The dynamic underwater chemistry seen in nature is inspiring for the next generation of eco-friendly nanochemistry. In this context, green synthesis of size-tailored nanoparticles in a facile and scalable manner via a dynamic process is an interesting challenge. Simulating the volcano-induced dynamic chemistry of the deep ocean, here we demonstrate the Leidenfrost dynamic chemistry occurring in an underwater overheated confined zone as a new tool for customized creation of nanoclusters of zinc peroxide. The hydrodynamic nature of the phenomenon ensures eruption of the nanoclusters towards a much colder region, giving rise to growth of monodisperse, size-tailored nanoclusters. Such nanoparticles are investigated in terms of their cytotoxicity on suspension and adherent cells to prove their applicability as cancer nanotherapeutics. Our research can pave the way for employment of the dynamic green nanochemistry in facile, scalable fabrication of size-tailored nanoparticles for biomedical applications.

Indexed as

AnimalsCell LineCell Line, TumorCell SurvivalGreen Chemistry TechnologyHot TemperatureHT29 CellsHumansJurkat CellsLeukocytes, MononuclearMetal NanoparticlesMiceNanomedicineNeoplasmsPeroxidesU937 CellsPeroxidesZinc

Identifiers

PMID28497789
PMCPMC5437293

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.