Evidence map›Paper›PMID 28497525›Full record

ArticleAmerican journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons2017

Risk of End-Stage Renal Disease in HIV-Positive Potential Live Kidney Donors.

A D Muzaale, K N Althoff, C J Sperati, A G Abraham, L M Kucirka, A B Massie, M M Kitahata, M A Horberg, A C Justice, M J Fischer and 16 more

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 36 citations in OpenAlex.

  1. Review
  2. Non-Standard Risk Donors and Risk of Donor-Derived Infections: From Evaluation to Therapeutic Management.Transplant international : official journal of the European Society for Organ Transplantation · 2024
    Review
  3. Article
  4. Review
  5. Article
  6. Review
  7. Organ transplantation in persons with HIV.AIDS (London, England) · 2020
    Review
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

26 authors at 14 institutions in 4 countries.

A D MuzaaleDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD.ORCID http://orcid.org/0000-0002-3287-6061
K N AlthoffDepartment of Epidemiology, Johns Hopkins School of Public Health, Baltimore, MD.
C J SperatiDepartment of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD.
A G AbrahamDepartment of Epidemiology, Johns Hopkins School of Public Health, Baltimore, MD.
L M KucirkaDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD.
A B MassieDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD.
M M KitahataUniversity of Washington Center for AIDS Research, Seattle, WA.
M A HorbergMid-Atlantic Permanente Institute, Rockville, MD.
A C JusticeVeterans Affairs Connecticut Healthcare System, West Haven, CT.
M J FischerJesse Brown VA Medical Center and Hines VA Hospital, Chicago, IL.
M J SilverbergKaiser Permanente Division of Research, Oakland, CA.
A A ButtHamad Healthcare Quality Institute, Hamad Medical Corporation, Doha, Qatar.
S L BoswellFenway Health HIV Cohort, Boston, MA.
A R RachlisInfectious Diseases Division, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada.
A M MayorUniversidad Central del Caribe, Bayamón, PR.
M J GillSouthern Alberta HIV Clinic, Sheldon M. Chumir Health Centre, Calgary, Alberta, Canada.
J J EronUniversity of North Carolina, HIV Clinic Cohort, Chapel Hill, NC.
S NapravnikUniversity of North Carolina, HIV Clinic Cohort, Chapel Hill, NC.
D R DrozdThe Polyclinic Madison Center, Seattle, WA.
J N MartinDepartment of Epidemiology and Biostatistics, University of California, San Francisco, CA.
R J BoschDepartment of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA.
C M DurandDepartment of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD.
J E LockeDepartment of Surgery, University of Alabama, Birmingham, AL.
R D MooreDepartment of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD.
G M LucasDepartment of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD.
D L SegevDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD.
Johns Hopkins University · USKaiser Permanente · USUniversity of North Carolina at Chapel Hill · USAlberta Hip and Knee Clinic · CACentral University of the Caribbean · PRCornell University · USFenway Health · USHarvard University · USJesse Brown VA Medical Center · USSunnybrook Health Science Centre · CAUniversity of Alabama at Birmingham · USUniversity of California, San Francisco · USUniversity of Washington · USVA Connecticut Healthcare System · US

Funding

Statistical and Data Management Center (SDMC), AIDS Clinical Trials Group (ACTG)UM1AI068634 · NIAID · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · PI Marlene Ann Cooper, Michael David Hughes · 2011 to 2026
$246.6M
WOMEN'S HEALTH AGENDAU01AI038858 · NIAID · SOCIAL AND SCIENTIFIC SYSTEMS, INC. · PI BENSON, CONSTANCE ANN · 1996 to 2008
$157.5M
AIDS Clinical Trials Group NetworkU01AI068636 · NIAID · SOCIAL AND SCIENTIFIC SYSTEMS, INC. · PI KURITZKES, DANIEL R. · 2006 to 2010
$147.1M
UCSF CLINICAL AND TRANSLATIONAL SCIENCE INSTITUTEUL1RR024131 · NCRR · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI JOHNSTON, S. CLAIBORNE · 2006 to 2011
$111.2M
University of Washington/Fred Hutch Center for AIDS ResearchP30AI027757 · NIAID · UNIVERSITY OF WASHINGTON · PI EDWIN ROBERTO ORELLANA · 1988 to 2026
$104.9M
Unsolicited R24 for the CFAR-Network of Integrated Clinical Sciences, CNICSR24AI067039 · NIAID · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Michael S. Saag · 2006 to 2026
$99.4M
Virology CoreP30AI027763 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MALLORY O JOHNSON · 1988 to 2026
$93.6M
Virology CoreP30AI027767 · NIAID · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Latesha Ellen Elopre · 1988 to 2026
$84.1M
STATISTICAL AND DATA MANAGEMENT CENTERU01AI038855 · NIAID · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI HUGHES, MICHAEL DAVID · 1996 to 2006
$78.1M
Engaging University of California Stakeholders for Biorespository ResearchUL1TR000004 · NCATS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI GRANDIS, JENNIFER RUBIN · 2012 to 2015
$78.0M
Studies of Ocular Complications of AIDS - Coordinating CenterU10EY008057 · NEI · JOHNS HOPKINS UNIVERSITY · PI VAN NATTA, MARK L · 1988 to 2012
$78.0M
Virology, Immunology, and Microbiology CoreP30AI050410 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI DAVID M. MARGOLIS · 2001 to 2026
$76.9M
Intramural NIH HHS Z01 CP010176NCATS NIH HHS KL2 TR000421NCATS NIH HHS KL2 TR002317NCATS NIH HHS UL1 TR000004NCATS NIH HHS UL1 TR000083NCATS NIH HHS UL1 TR000454NCI NIH HHS N02 CP055504NCI NIH HHS R01 CA165937NCRR NIH HHS M01 RR000052NCRR NIH HHS UL1 RR024131NEI NIH HHS K23 EY013707NEI NIH HHS U10 EY008052NEI NIH HHS U10 EY008057NEI NIH HHS U10 EY008067NIAAA NIH HHS R01 AA016893NIAAA NIH HHS U01 AA013566NIAAA NIH HHS U01 AA020790NIAAA NIH HHS U24 AA020794NIAID NIH HHS K01 AI093197NIAID NIH HHS K24 AI065298NIAID NIH HHS P30 AI027757NIAID NIH HHS P30 AI027763NIAID NIH HHS P30 AI027767NIAID NIH HHS P30 AI036219NIAID NIH HHS P30 AI050410NIAID NIH HHS P30 AI054999NIAID NIH HHS P30 AI094189NIAID NIH HHS R24 AI067039NIAID NIH HHS U01 AI031834NIAID NIH HHS U01 AI034989NIAID NIH HHS U01 AI034993NIAID NIH HHS U01 AI034994NIAID NIH HHS U01 AI035004NIAID NIH HHS U01 AI035039NIAID NIH HHS U01 AI035040NIAID NIH HHS U01 AI035041NIAID NIH HHS U01 AI035042NIAID NIH HHS U01 AI037613NIAID NIH HHS U01 AI037984NIAID NIH HHS U01 AI038855NIAID NIH HHS U01 AI038858NIAID NIH HHS U01 AI042590NIAID NIH HHS U01 AI068634NIAID NIH HHS U01 AI068636NIAID NIH HHS U01 AI069432NIAID NIH HHS U01 AI069434NIAID NIH HHS U01 AI069918NIAID NIH HHS U01 AI103390NIAID NIH HHS U01 AI103397NIAID NIH HHS U01 AI103401NIAID NIH HHS U01 AI103408NIAID NIH HHS UM1 AI035043NIAID NIH HHS UM1 AI068634NICHD NIH HHS U01 HD032632NIDA NIH HHS F31 DA037788NIDA NIH HHS K24 DA000432NIDA NIH HHS K24 DA035684NIDA NIH HHS R01 DA004334NIDA NIH HHS R01 DA011602NIDA NIH HHS R01 DA012568NIDA NIH HHS R01 DA026770NIDA NIH HHS U01 DA036935NIDDK NIH HHS K24 DK101828NIDDK NIH HHS R01 DK096008NIGMS NIH HHS T32 GM007309NIMHD NIH HHS G12 MD007583NIMHD NIH HHS U54 MD007587NIMH NIH HHS P30 MH062246
6 · The paper itself

Abstract

New federal regulations allow HIV-positive individuals to be live kidney donors; however, potential candidacy for donation is poorly understood given the increased risk of end-stage renal disease (ESRD) associated with HIV infection. To better understand this risk, we compared the incidence of ESRD among 41 968 HIV-positive participants of North America AIDS Cohort Collaboration on Research and Design followed for a median of 5 years with the incidence of ESRD among comparable HIV-negative participants of National Health and Nutrition Examination III followed for a median of 14 years. We used risk associations from multivariable Cox proportional hazards regression to derive cumulative incidence estimates for selected HIV-positive scenarios (no history of diabetes, hypertension, AIDS, or hepatitis C virus coinfection) and compared these estimates with those from similarly selected HIV-negative scenarios. For 40-year-old HIV-positive individuals with health characteristics that were similar to those of age-matched kidney donors, viral load <400 copies/mL, and CD4

Indexed as

Living DonorsAdultCase-Control StudiesFemaleFollow-Up StudiesGlomerular Filtration RateGraft RejectionGraft SurvivalHIV-1HIV InfectionsHIV SeropositivityHumansIncidenceKidney Failure, ChronicKidney Function TestsKidney Transplantationclinical research/practicedonors and donation: livinginfection and infectious agentsinfectious diseasekidney transplantation/nephrologyviral: human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS)

Identifiers

PMID28497525
PMCPMC5489376
OpenAlexW2613773313

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.