Evidence map›Paper›PMID 28497395›Full record

ArticleChinese journal of integrative medicine2017

Cardioprotective effects of Qishen Granule () on sarcoplasmic reticulum Ca

Ling-Hui Lu, Chun Li, Qi-Yan Wang, Qian Zhang, Yi Zhang, Hui Meng, Yong Wang, Wei Wang

Abstract read
PubMed Publisher
In one paragraph

Article in Chinese journal of integrative medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. A Network Pharmacology Approach to Explore the Mechanisms of Qishen Granules in Heart Failure.Medical science monitor : international medical journal of experimental and clinical research · 2019
    Article
  5. Antiapoptosis and Antifibrosis Effects ofBioMed research international · 2019
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Ling-Hui LuSchool of Preclinical Medicine, Beijing University of Chinese Medicine, Beijing, 100029, China.
Chun LiModern Research Center for Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing, 100029, China.
Qi-Yan WangSchool of Life Sciences, Beijing University of Chinese Medicine, Beijing, 100029, China.
Qian ZhangSchool of Preclinical Medicine, Beijing University of Chinese Medicine, Beijing, 100029, China.
Yi ZhangModern Research Center for Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing, 100029, China.
Hui MengModern Research Center for Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing, 100029, China.
Yong WangSchool of Life Sciences, Beijing University of Chinese Medicine, Beijing, 100029, China.
Wei WangSchool of Preclinical Medicine, Beijing University of Chinese Medicine, Beijing, 100029, China. wangwei26960@126.com.
Beijing University of Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo assess the effects of Qishen Granule (, QSG) on sarcoplasmic reticulum (SR) Ca

methodsHF rat models were induced by left anterior descending coronary artery ligation surgery and high-fat diet feeding. Rats were randomly divided into sham (n=10), model (n=10), QSG (n=12, 2.2 g/kg daily) and metoprolol groups (n=12, 10.5 mg/kg daily). The therapeutic effects of QSG were evaluated by echocardiography and blood lipid testing. Intracellular Ca

resultsHF model of rats developed ventricular remodeling accompanied with calcium overload and defective Ca

conclusionQSG restored SR Ca

Indexed as

AnimalsCalciumCardiotonic AgentsDrugs, Chinese HerbalElectrocardiographyFibrosisHeart FailureIntracellular SpaceLipid MetabolismMaleMyocardiumRats, Sprague-DawleyRyanodine Receptor Calcium Release ChannelSarcoplasmic ReticulumSarcoplasmic Reticulum Calcium-Transporting ATPasesCalciumCardiotonic AgentsDrugs, Chinese HerbalRyanodine Receptor Calcium Release ChannelSarcoplasmic Reticulum Calcium-Transporting ATPasesCa2+ handlingChinese medicineheart failureQishen Granuleryanodine receptor 2sarco-endoplasmic reticulum ATPase 2a

Identifiers

PMID28497395
OpenAlexW2612390676

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.