ArticleNeuroradiology2017
Arterial tortuosity in patients with spontaneous cervical artery dissection.
Article in Neuroradiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 3 of them syntheses that pooled it.
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Who cites it
18 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Cervical arteries tortuosity and its association with dissection: A systematic review and meta-analysis.Medicine · 2025Pooled it
- Recurrence of cervical artery dissection: A systematic review and meta-analysis.International journal of stroke : official journal of the International Stroke Society · 2024Pooled it
- Spontaneous cervical artery dissection: is it really a connective tissue disease? A comprehensive review.Frontiers in neurology · 2023Pooled it
- Arterial Tortuosity and Its Correlation with White Matter Hyperintensities in Acute Ischemic Stroke.Neural plasticity · 2022Trial
- Early change and new onset of vascular pathology in cervical artery dissection: implications for surveillance.European stroke journal · 2026Article
- Origin-entry geometry and left-sided V1 vertebral artery tortuosity: a retrospective cross-sectional CT angiography study.Neuroradiology · 2026Article
- Association between cervicocerebral artery dissection and tortuosity - a review on quantitative and qualitative assessment.Acta neurochirurgica · 2024Review
- Cervical artery tortuosity-a reliable semi-automated magnetic resonance-based method.Quantitative imaging in medicine and surgery · 2024Article
- Unraveling the Links between Chronic Inflammation, Autoimmunity, and Spontaneous Cervicocranial Arterial Dissection.Journal of clinical medicine · 2023Review
- The proximity between styloid process and internal carotid artery as a possible risk factor for dissection: a case-control study.Neuroradiology · 2023Article
- Carotid tortuosity is associated with extracranial carotid artery aneurysms.Quantitative imaging in medicine and surgery · 2022Article
- Aortic tortuosity in Turner syndrome is associated with larger ascending aorta.The international journal of cardiovascular imaging · 2022Article
- Diabetes, hypertension, smoking, and hyperlipidemia as risk factors for spontaneous cervical artery dissection: Meta-analysis of case-control studies.Current journal of neurology · 2022Review
- Association between carotid artery dissection and vascular tortuosity: a case-control study.Neuroradiology · 2022Article
- Utility of Pipeline embolization device for emergency recanalization of a dissecting carotid tonsillar loop: illustrative cases.Journal of neurosurgery. Case lessons · 2021Article
- Changes in internal carotid and vertebral arterial wall stiffness with head movement can be detected with shear wave elastography.The Journal of manual & manipulative therapy · 2020Observational
- Comparability of semiautomatic tortuosity measurements in the carotid artery.Neuroradiology · 2019Article
- Cervical artery dissection after sports - An analytical evaluation of 190 published cases.European stroke journal · 2017Article
Corrections and comments
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Authors and funding
16 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe aim of this study was to test the hypothesis that patients with spontaneous cervical artery dissection (CeAD) have increased arterial tortuosity, and the objective quantification of such a tortuosity may aid in the identification of subjects at increased risk of disease.
methodsIn the setting of a hospital-based, case-control study, we used the vertebral tortuosity index (VTI) measured on magnetic resonance angiography, a validated method for the assessment and quantification of arterial tortuosity, to compare the degree of tortuosity in a series of consecutive patients with spontaneous CeAD and of age- and sex-matched patients with ischemic stroke unrelated to CeAD (non-CeAD IS) and stroke-free subjects.
resultsThe study group was composed of 102 patients with CeAD (mean age, 44.5 ± 7.8 years; 66.7% men), 102 with non-CEAD IS, and 102 stroke-free subjects. The VTI was higher in the group of patients with CeAD (median, 7.3; 25th-75th percentile, 10.2) compared with that of non-CeAD IS (median, 3.4; 25th-75th percentile, 4.4) and of stroke-free subjects (median, 4.0; 25th-75th percentile, 2.9; p ≤ 0.001), and was independently associated to the risk of CeAD (OR, 1.18; 95% CI, 1.09-1.29) in multivariable regression analysis. The degree of tortuosity also tended to be higher in CeAD patients who experienced short-term recurrence (5.8%; median, 20.2; 25th-75th percentile, 31.2) than in those without recurrent events (median, 7.2; 25th-75th percentile, 9.4; p = 0.074).
conclusionCeAD patients exhibit increased arterial tortuosity. This might have potential implications for better understanding of the pathophysiology of the disease as well as clinical utility in evaluation, prognostication, and decision-making of affected individuals.
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