ArticlePediatric nephrology (Berlin, Germany)2017
Evaluation of the coronary circulation and calcification in children on regular hemodialysis.
Article in Pediatric nephrology (Berlin, Germany), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
8 citing papers in PubMed, 12 citations in OpenAlex.
- The Diagnostic Value of Plasma NETs Levels and iCEB in Silent Myocardial Ischemia in Maintenance Hemodialysis Patients.Journal of inflammation research · 2025Article
- Vascular ageing: moving from bench towards bedside.European journal of preventive cardiology · 2023Article
- Cardiovascular Calcification Heterogeneity in Chronic Kidney Disease.Circulation research · 2023Review
- Reducing the burden of cardiovascular disease in children with chronic kidney disease: prevention vs. damage limitation.Pediatric nephrology (Berlin, Germany) · 2021Review
- Cardiovascular risk factors in children on dialysis: an update.Pediatric nephrology (Berlin, Germany) · 2020Review
- Glomerular disease patients have higher odds not to reach quality targets in chronic dialysis compared with CAKUT patients: analyses from a nationwide German paediatric dialysis registry.Pediatric nephrology (Berlin, Germany) · 2019Article
- Early Vascular Ageing and Cellular Senescence in Chronic Kidney Disease.Computational and structural biotechnology journal · 2019Review
- Early predictors of cardiac dysfunction in Egyptian children with chronic kidney disease.Annals of pediatric cardiologyArticle
Corrections and comments
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Authors and funding
5 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe objective of this study was to evaluate the coronary circulation and calcification in children with end-stage renal disease (ESRD) on hemodialysis.
methodsA total of 50 children with ESRD and 50 healthy controls were enrolled in the study. Cardiac functions and coronary blood flow were evaluated with conventional and tissue Doppler echocardiography. Coronary artery calcification (CAC) was evaluated using high-resolution multidetector computed tomography (CT).
resultsThe hyperemic coronary flow volume (CFV) and coronary flow reserve were significantly lower in the patient group than in the controls, while there was no significant difference in the baseline CFV between the two groups. Hypertension was present in 60% and CAC was observed in 20% of the children in the patient group. CAC was present in 30% of the children in the hypertensive subgroup. The left ventricle myocardial performance index (LV MPI), CAC score, duration of hypertension and level of diastolic blood pressure were independent predictors of the coronary blood flow, and LV MPI, serum parathyroid hormone, duration of dialysis and E'/A' mitral valve were independent predictors of coronary calcification.
conclusionHigh diastolic blood pressure, long duration of hypertension, high LV MPI and increased CAC scores are independent risk factors for impaired coronary blood flow in children with ESRD.
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Registered trials
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