ArticleBiological psychiatry. Cognitive neuroscience and neuroimaging2017
Vulnerability to Depression in Youth: Advances from Affective Neuroscience.
Article in Biological psychiatry. Cognitive neuroscience and neuroimaging, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 77 papers, 4 of them syntheses that pooled it.
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Who cites it
77 citing papers in PubMed, 4 syntheses or guidelines pooled it, 116 citations in OpenAlex.
- A Systematic Review of Parent Socialization of Negative Affect in Clinical Child Samples: Relations to Youth Emotion Regulation Abilities.Clinical child and family psychology review · 2024Pooled it
- The effects of stress on reward responsiveness: a systematic review and preliminary meta-analysis of the event-related potential literature.Cognitive, affective & behavioral neuroscience · 2024Pooled it
- Parent Emotion Socialization and Positive Emotions in Child and Adolescent Clinical Samples: A Systematic Review and Call to Action.Clinical child and family psychology review · 2022Pooled it
- Neuroimaging predictors of onset and course of depression in childhood and adolescence: A systematic review of longitudinal studies.Developmental cognitive neuroscience · 2019Pooled it
- A pilot randomized controlled trial of a brief intervention targeting positive valence systems function to prevent internalizing symptoms in college students.Journal of consulting and clinical psychology · 2025Trial
- Targeting positive valence systems function in children of mothers with depressive symptoms: A pilot randomized trial of an RDoC-Informed preventive intervention.Behaviour research and therapy · 2023Trial
- Preschool-Onset Major Depressive Disorder is Characterized by Electrocortical Deficits in Processing Pleasant Emotional Pictures.Journal of abnormal child psychology · 2020Trial
- Linking childhood adversity with borderline and depressive symptoms: the role of reward processing.European journal of psychotraumatology · 2026Article
- Editorial: Mechanism-specific developmental windows of opportunity in the prevention of youth psychopathology.Journal of child psychology and psychiatry, and allied disciplines · 2026Article
- Early parenting is associated with the development of neural reward responsiveness from childhood through adolescence.Communications psychology · 2026Article
- Low reward responsiveness as a moderator of chronic stress effects on depressive symptoms in adolescents: An examination of monetary and social rewards.Journal of affective disorders · 2026Article
- Reduced amygdala habituation to anticipated social rejection in youth with major depressive disorder.Journal of affective disorders · 2026Article
- Reward-specific learning parameters change across normative adolescent development and are blunted in youth with high risk for depression.Journal of child psychology and psychiatry, and allied disciplines · 2026Article
- Neural reactivity to infant faces and trait mindfulness as prospective predictors of postpartum depressive symptoms.Cognitive, affective & behavioral neuroscience · 2026Article
- Parental anhedonic versus non-anhedonic depressive symptoms and children's reward processing.Journal of experimental child psychology · 2026Article
- The interplay of reward responsiveness and socioeconomic disadvantage in the prospective prediction of depression symptoms in youth.Psychological medicine · 2025Article
- Behavioral and neural dysfunctions in reward-related cognitive control among adolescents with major depressive disorder.Psychological medicine · 2025Article
- Intergenerational transmission of depression: Testing a comprehensive set of putative mediators.Journal of psychopathology and clinical science · 2025Article
- Exploring Neural Markers of Reward and Loss Processing and Problematic Parenting Styles A Mothers With and Without Histories of Depression.Developmental psychobiology · 2025Article
- Developmental cascades from maternal depressive symptoms in childhood to adolescents' friendship quality: A 13-year longitudinal study.Developmental psychology · 2025Article
17 more citing papers are in PubMed but not listed here.
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
Vulnerability models of depression posit that individual differences in trait-like vulnerabilities emerge early in life and increase risk for the later development of depression. In this review, we summarize advances from affective neuroscience using neural measures to assess vulnerabilities in youth at high risk for depression due to parental history of depression or temperament style, as well as prospective designs evaluating the predictive validity of these vulnerabilities for symptoms and diagnoses of depression across development. Evidence from multiple levels of analysis indicates that healthy youth at high risk for depression exhibit abnormalities in components of the Research Domain Criteria (RDoC) positive valence systems, including blunted activation in the striatum during reward anticipation and feedback, and that some of these measures can be used to predict later symptoms. In addition, alterations in components of RDoC's negative valence systems, including neural processing of sadness, loss, and threat, have been observed in risk for depression, though effects appear to be more task and method dependent. Within the social processes domain, preliminary evidence indicates that neural processing of social feedback, including heightened reactivity to exclusion and blunted response to social reward, may be related to depression vulnerability. These studies indicate that affective neuroscience can inform understanding of developmental pathways to depression and identify altered emotional processing among youth at high risk. We provide an integrated summary of consistent findings from this literature, along with recommendations for future directions and implications for early intervention.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.