ArticleJournal of renal injury prevention2017
An update on diabetic kidney disease, oxidative stress and antioxidant agents.
Article in Journal of renal injury prevention, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03711682 (Hypoglycemic Effect of Cinnamomum Verum in Type 2 Diabetic Patients in the Municipality of Comasagua), which is not on this map. Cited by 34 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Hypoglycemic Effect of Cinnamomum Verum in Type 2 Diabetic Patients in the Municipality of Comasagua
Who cites it
34 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Renoprotective effects of the ginger (Zingiber officinale) on Diabetic kidney disease, current knowledge and future direction: a systematic review of animal studies.BMC complementary medicine and therapies · 2022Pooled it
- Calebin A mitigates oxidative stress and inflammation in diabetic nephropathy via Nrf2/HO-1 and NF-κB signaling pathways.Journal of diabetes investigation · 2026Article
- Article
- Association of glycemic variability with oxidative stress and AGE accumulation in type 2 diabetes.Scientific reports · 2025Article
- Breastfeeding was associated with lower risks of maternal postpartum hypertension and diabetes mellitus: A systematic review and meta-analysis.World journal of diabetes · 2025Article
- The Role of Mitochondrial AKT1 Signaling in Renal Tubular Injury of Metabolic Syndrome.Kidney international reports · 2025Article
- Phloretamide Protects against Diabetic Kidney Damage and Dysfunction in Diabetic Rats by Attenuating Hyperglycemia and Hyperlipidemia, Suppressing NF-κβ, and Upregulating Nrf2.Pharmaceutics · 2024Article
- Cinnamon: a nutraceutical supplement for the cardiovascular system.Archives of medical sciences. Atherosclerotic diseases · 2024Article
- Article
- Article
- Protective effect of eriodictyol against hyperglycemia-induced diabetic nephropathy in rats entails antioxidant and anti-inflammatory effects mediated by activating Nrf2.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2023Article
- Antioxidant Effect of the Ethyl Acetate Extract ofPlants (Basel, Switzerland) · 2023Article
- Article
- A Review of Medicinal Plants with Renoprotective Activity in Diabetic Nephropathy Animal Models.Life (Basel, Switzerland) · 2023Review
- Mechanism of the antidiabetic action ofFrontiers in nutrition · 2023Review
- Gingerol, a Natural Antioxidant, Attenuates Hyperglycemia and Downstream Complications.Metabolites · 2022Review
- Increased Expression of Circulating Stress Markers, Inflammatory Cytokines and Decreased Antioxidant Level in Diabetic Nephropathy.Medicina (Kaunas, Lithuania) · 2022Article
- 6-Gingerol, a Bioactive Compound of Ginger Attenuates Renal Damage in Streptozotocin-Induced Diabetic Rats by Regulating the Oxidative Stress and Inflammation.Pharmaceutics · 2021Article
- Leaf Extracts ofPlants (Basel, Switzerland) · 2021Article
- Maackiain Protects the Kidneys of Type 2 Diabetic Rats via Modulating the Nrf2/HO-1 and TLR4/NF-κB/Caspase-3 Pathways.Drug design, development and therapy · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Diabetes mellitus is a metabolic disease that is defined by relative or absolute deficiency of insulin secretion. Diabetic kidney disease seems to be one of the most frequent complications of diabetes mellitus. Based on evidence, increased free-radical formation and/or diminished antioxidant defenses induce oxidative stress that is implicated in the pathogenesis of diabetic kidney disease. It is evident that diabetic state induces oxidative stress through different signaling pathways as well as reactive oxygen species (ROS) formation that attributes to the activation of various downstream signaling cascade leading to structural the way to structural and functional changes in kidney.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.