Evidence map›Paper›PMID 28497028›Full record

ArticleFrontiers in cellular and infection microbiology2017

Inactive Gingipains from

Izabela Glowczyk, Alicia Wong, Barbara Potempa, Olena Babyak, Maciej Lech, Richard J Lamont, Jan Potempa, Joanna Koziel

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 35 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. In Vitro Infection of Human Macrophages withInternational journal of molecular sciences · 2025
    Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Review
  11. Review
  12. Review
  13. Article
  14. The Effects ofFrontiers in immunology · 2021
    Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Journal of oral microbiology · 2018
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 3 countries.

Izabela GlowczykDepartment of Microbiology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian UniversityKrakow, Poland.
Alicia WongDepartment of Microbiology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian UniversityKrakow, Poland.
Barbara PotempaCenter for Oral Health and Systemic Disease, University of Louisville School of Dentistry, University of LouisvilleLouisville, KY, USA.
Olena BabyakDepartment of Microbiology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian UniversityKrakow, Poland.
Maciej LechDepartment of Microbiology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian UniversityKrakow, Poland.
Richard J LamontCenter for Oral Health and Systemic Disease, University of Louisville School of Dentistry, University of LouisvilleLouisville, KY, USA.
Jan PotempaDepartment of Microbiology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian UniversityKrakow, Poland.
Joanna KozielDepartment of Microbiology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian UniversityKrakow, Poland.
Jagiellonian University · PLUniversity of Louisville · USLudwig-Maximilians-Universität München · DE

Funding

P.gingivalis Interactions with Gingival Epithelial CellsR37DE011111 · NIDCR · UNIVERSITY OF LOUISVILLE · PI LAMONT, RICHARD J · 2009 to 2018
$3.6M
Role of JAKs in innate responses to P. gingivalisR01DE017921 · NIDCR · UNIVERSITY OF LOUISVILLE · PI LAMONT, RICHARD J · 2010 to 2019
$3.3M
Blocking of IL-6 function to prevent Pg mediated Th17 responseR21DE023207 · NIDCR · UNIVERSITY OF LOUISVILLE · PI POTEMPA, JAN S · 2013 to 2014
$413k
NIDCR NIH HHS R01 DE017921NIDCR NIH HHS R21 DE023207NIDCR NIH HHS R37 DE011111
6 · The paper itself

Abstract

Gingipain cysteine proteases are considered key virulence factors of

Indexed as

Adhesins, BacterialBacterial InfectionsBone ResorptionCD4-Positive T-LymphocytesCell DifferentiationCell ProliferationCysteine EndopeptidasesCytokinesDendritic CellsFimbriae, BacterialGene Expression RegulationGingipain Cysteine EndopeptidasesGingivaHumansInflammationInterleukin-21Adhesins, BacterialCysteine EndopeptidasesCytokinesGingipain Cysteine EndopeptidasesInterleukin-21Interleukin-23Interleukin-6InterleukinsVirulence Factorsdendritic cellsgingipainsIL-6P. gingivalisTh17

Identifiers

PMID28497028
PMCPMC5406403
OpenAlexW2609672290

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.