The Transcription Regulator Krüppel-Like Factor 4 and Its Dual Roles of Oncogene in Glioblastoma and Tumor Suppressor in Neuroblastoma.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.

1. Tracing the origins of glioblastoma by investigating the role of gliogenic and related neurogenic genes/signaling pathways in GBM development: a systematic review.World journal of surgical oncology · 2022
   Pooled it
2. The KLF4-inflammatory pathway is associated with paraquat-induced pulmonary injury and early pro-fibrotic responses.Biochemistry and biophysics reports · 2026
   Article
3. Controlling Biogenesis and Engineering of Exosomes to Inhibit Growth and Promote Death in Glioblastoma Multiforme.Brain sciences · 2026
   Review
4. TransMarker: Unveiling dynamic network biomarkers in cancer progression through cross-state graph alignment and optimal transport.PLoS computational biology · 2025
   Article
5. Impact of G1 phase kinetics on the acquisition of stemness in cancer cells: the critical role of cyclin D.Molecular biology reports · 2025
   Review
6. PDCD10 Is a Key Player in TMZ-Resistance and Tumor Cell Regrowth: Insights into Its Underlying Mechanism in Glioblastoma Cells.Cells · 2024
   Article
7. Bioinformatic Evaluation ofGenes · 2024
   Article
8. Krüppel-like Factors 4 and 5 in Colorectal Tumorigenesis.Cancers · 2023
   Review
9. The Molecular and Cellular Strategies of Glioblastoma and Non-Small-Cell Lung Cancer Cells Conferring Radioresistance.International journal of molecular sciences · 2022
   Review
10. Epigenomic and enhancer dysregulation in uterine leiomyomas.Human reproduction update · 2022
    Review
11. Pluripotency Stemness and Cancer: More Questions than Answers.Advances in experimental medicine and biology · 2022
    Article
12. Human Pluripotent Stem Cells-Based Therapies for Neurodegenerative Diseases: Current Status and Challenges.Cells · 2020
    Review
13. Mapping DNA interaction landscapes in psoriasis susceptibility loci highlights KLF4 as a target gene in 9q31.BMC biology · 2020
    Article
14. Identification of Cancer Stem Cell Subpopulations in Head and Neck Metastatic Malignant Melanoma.Cells · 2020
    Article
15. Porf-2 Inhibits Tumor Cell Migration Through the MMP-2/9 Signaling Pathway in Neuroblastoma and Glioma.Frontiers in oncology · 2020
    Article
16. Ranking genomic features using an information-theoretic measure of epigenetic discordance.BMC bioinformatics · 2019
    Article
17. Methylation status of KLF4 and HS3ST2 genes as predictors of endometrial cancer and hyperplastic endometrial lesions.International journal of molecular medicine · 2018
    Article
18. Stemness and clinical features in relation to the subventricular zone in diffuse lower-grade glioma: an exploratory study.Neuro-oncology advances
    Article

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

Authors and funding

1 author at 1 institution in 1 country.

Funding

Abstract

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