Evidence map›Paper›PMID 28496562›Full record

ArticleCurrent cardiovascular risk reports2016

Epigenetics of Lipid Phenotypes.

Sergi Sayols-Baixeras, Marguerite R Irvin, Donna K Arnett, Roberto Elosua, Stella W Aslibekyan

Open access · greenAbstract read
In one paragraph

Article in Current cardiovascular risk reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 28 citations in OpenAlex.

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  14. A preliminary study of the association between theMolecular biology research communications · 2018
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Sergi Sayols-BaixerasCardiovascular Epidemiology and Genetics Group, Institut Hospital del Mar d'Investigacions Mediques (IMIM), Dr. Aiguader, 88, Barcelona 08003, Spain, Universitat Pompeu Fabra (UPF), Barcelona 08003, Spain, (tel) 34-93-316-07-27, (fax) 34-93-316-04-10.
Marguerite R IrvinDepartment of Epidemiology, University of Alabama at Birmingham, 1665 University Blvd, RPHB 220F, Birmingham, AL 35205, USA, (tel) 1-205-975-7672, (fax)1-205-975-3329.
Donna K ArnettCollege of Public Health, University of Kentucky, 111 Washington Avenue, Lexington, KY 40536, USA, (tel) 1-859-257-5678, (fax) 1-859-257-8811.
Roberto ElosuaCardiovascular Epidemiology and Genetics Group, Institut Hospital del Mar d'Investigacions Mediques (IMIM), Dr. Aiguader, 88, Barcelona 08003, Spain, (tel) 34-93-316-08-00, (fax) 34-93-316-04-10.
Stella W AslibekyanDepartment of Epidemiology, University of Alabama at Birmingham, 1665 University Blvd, RPHB 230J, Birmingham, AL 35205, USA, (tel) 1-205-975-7675, (fax) 1-205-975-3329.
University of Alabama at Birmingham · USHospital del Mar Research Institute · ESPompeu Fabra University · ESUniversity of Kentucky · US

Funding

Epigenetic Determinants of Lipid Response to Dietary Fat and FenofibrateR01HL104135 · NHLBI · UNIVERSITY OF KENTUCKY · PI ARNETT, DONNA K · 2010 to 2015
$5.5M
NHLBI NIH HHS R01 HL104135
6 · The paper itself

Abstract

Dyslipidemia is a well-established risk factor for cardiovascular disease, the main cause of death worldwide. Blood lipid profiles are patterned by both genetic and environmental factors. In recent years, epigenetics has emerged as a paradigm that unifies these influences. In this review, we have summarized the latest evidence implicating epigenetic mechanisms-DNA methylation, histone modification, and regulation by RNAs-in lipid homeostasis. Key findings have emerged in a number of novel epigenetic loci located in biologically plausible genes (e.g.

Indexed as

CholesterolEpigeneticsLipidsMethylationTriglycerides

Identifiers

PMID28496562
PMCPMC5421987
OpenAlexW2507656315

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.