Evidence map›Paper›PMID 28496532›Full record

ArticleGastroenterology research2017

Lack of Association Between the Clinical Outcome of

Ahmed Dirweesh, Chikezie Alvarez, Muhammad Khan, Bushra Ambreen, Rishitha Yelisetti, Shaikh Fawwad Hamiz, Sana Zia, Muhammad Tahir, Vincent A DeBari, Donald Christmas and 1 more

Open access · diamondAbstract read
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Article in Gastroenterology research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Observational
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Ahmed DirweeshDepartment of Internal Medicine, Seton Hall University, Saint Francis Medical Center, Trenton, NJ, USA.
Chikezie AlvarezDepartment of Internal Medicine, Seton Hall University, Saint Francis Medical Center, Trenton, NJ, USA.
Muhammad KhanDepartment of Internal Medicine, Seton Hall University, Saint Francis Medical Center, Trenton, NJ, USA.
Bushra AmbreenDepartment of Internal Medicine, Seton Hall University, Saint Francis Medical Center, Trenton, NJ, USA.
Rishitha YelisettiDepartment of Internal Medicine, Seton Hall University, Saint Francis Medical Center, Trenton, NJ, USA.
Shaikh Fawwad HamizDepartment of Internal Medicine, Seton Hall University, Saint Francis Medical Center, Trenton, NJ, USA.
Sana ZiaDepartment of Internal Medicine, Seton Hall University, Saint Francis Medical Center, Trenton, NJ, USA.
Muhammad TahirDepartment of Internal Medicine, Seton Hall University, Saint Francis Medical Center, Trenton, NJ, USA.
Vincent A DeBariDepartment of Internal Medicine, School of Health and Medical Sciences, Seton Hall University, South Orange, NJ, USA.
Donald ChristmasDepartment of Internal Medicine, Seton Hall University, Saint Francis Medical Center, Trenton, NJ, USA.
Sara WallachDepartment of Internal Medicine, Seton Hall University, Saint Francis Medical Center, Trenton, NJ, USA.
Seton Hall University · USSaint Francis Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe purpose of this study was to compare the outcome of

methodsWe retrospectively reviewed records of all patients with CDI at our hospital from January 2011 to December 2016. Patients were evaluated for baseline characteristics, comorbidities, medications, disease severity, disease-related length of stay (LOS) from the diagnosis of CDI to discharge, need for surgical intervention, and disease-related mortality. Based on systemic steroids use, patients who were using steroids for different indications constituted the study population, and those with no steroids use were clustered as a control group.

resultsOf the 258 patients included, males were 127 (49%). Severe and severe-complicated CDI developed in 21/63 (33.3%) and 1/63 (1.6%) of patients on steroids (average daily dose of 20 mg), and in 73/195 (37.4%) and 5/195 (2.6%) of patients with no steroids use (P = 0.56 and P = 0.66, respectively). Surgical intervention was not required in the steroids group and 5/195 (2.7%) of patients not on steroids underwent bowel surgeries (P = 0.38). Mean LOS (days) was 11.6 ± 1.5 in the steroids group and 10.4 ± 0.7 in the no-steroids group (P = 0.4). CDI-related mortality occurred in 9/63(14.3%) of patients on steroids, and in 15/195 (7.7%) of patients not on steroids (P = 0.12; odds ratio (OR): 2; 95% confidence interval (CI): 0.8 - 4.8).

conclusionThere was no significant difference in the severity of CDI, need for surgical interventions, disease-related LOS and mortality in systemic steroids users compared to patients not on steroids.

Indexed as

Clostridium difficileSteroids

Identifiers

PMID28496532
PMCPMC5412544
OpenAlexW2606457261

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.