ArticleScientific reports2017
Clinical experience with the artificial bone graft substitute Calcibon used following curettage of benign and low-grade malignant bone tumors.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 17 citations in OpenAlex.
- Artificial Bone Graft Substitutes for Curettage of Benign and Low-Grade Malignant Bone Tumors: Clinical and Radiological Experience with Cerasorb.Indian journal of orthopaedics · 2023Article
- The effect of ROS-YAP crosstalk on osteoimmune response orchestrating osteogenesis.Cell cycle (Georgetown, Tex.) · 2023Article
- Recent advances in hydrogels-based osteosarcoma therapy.Frontiers in bioengineering and biotechnology · 2022Review
- Review of a new bone tumor therapy strategy based on bifunctional biomaterials.Bone research · 2021Review
- Biomedical Radioactive Glasses for Brachytherapy.Materials (Basel, Switzerland) · 2021Review
- Clinical Applications of Injectable Biomaterials.Advances in experimental medicine and biologyReview
- CRISPRa genome-wide screen identifies novel gene targets for osteogenic cell engineering.Journal of tissue engineeringArticle
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
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Abstract
Artificial bone graft substitutes, such as Calcibon, are becoming increasingly interesting as they do not cause donor site morbidity which is an advantage compared to autologous bone grafts. The aim of this study was to evaluate the efficacy and potential complications associated with the use of Calcibon. Twenty-seven patients with benign and low-grade malignant bone tumors were treated with curettage and refilling of the bony cavity. Based on the radiological classification system of Neer, these lesions only comprised Grade I lesions, describing cysts that only require curettage and filling, but no additional treatment. At a mean follow up of six months we observed radiological consolidation without resorption of the bone graft substitute. These observations were also made at a mean follow-up of 13 and 32 months, respectively. According to the classification system of Goslings and Gouma we observed six surgical complications. Summing up, Calcibon seems to be a reliable bone graft substitute with low complication rates. However, delayed resorption should be expected. Calcibon seems to be an alternative to autologous bone grafts or allografts in adequate indications.
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