Evidence map›Paper›PMID 28495950›Full record

ArticleAJNR. American journal of neuroradiology2017

Carotid Bulb Webs as a Cause of "Cryptogenic" Ischemic Stroke.

P I Sajedi, J N Gonzalez, C A Cronin, T Kouo, A Steven, J Zhuo, O Thompson, R Castellani, S J Kittner, D Gandhi and 1 more

Open access · bronzeAbstract read
In one paragraph

Article in AJNR. American journal of neuroradiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
61citing papers in PubMed, 1 pooled it
8.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

61 citing papers in PubMed, 1 synthesis or guideline pooled it, 137 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Safety and efficacy of staged bilateral carotid artery stenting for bilateral carotid webs.Journal of cerebrovascular and endovascular neurosurgery · 2026
    Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Cerebrovascular fibromuscular dysplasia.Therapeutic advances in neurological disorders · 2026
    Review
  14. Observational
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article

1 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 3 countries.

P I SajediFrom the Departments of Diagnostic Radiology and Nuclear Medicine (P.R., P.I.S., T.K., J.Z.).ORCID http://orcid.org/0000-0003-1589-9920
J N GonzalezNeurology (J.N.G., C.A.C., O.T., S.J.K.).ORCID http://orcid.org/0000-0002-0023-3280
C A CroninNeurology (J.N.G., C.A.C., O.T., S.J.K.).ORCID http://orcid.org/0000-0002-4303-5823
T KouoFrom the Departments of Diagnostic Radiology and Nuclear Medicine (P.R., P.I.S., T.K., J.Z.).ORCID http://orcid.org/0000-0003-2778-7205
A StevenDepartment of Diagnostic Radiology and Nuclear Medicine (A.S.), Ochsner Medical Center, New Orleans, Louisiana.ORCID http://orcid.org/0000-0001-5828-2969
J ZhuoFrom the Departments of Diagnostic Radiology and Nuclear Medicine (P.R., P.I.S., T.K., J.Z.).ORCID http://orcid.org/0000-0001-6637-701X
O ThompsonNeurology (J.N.G., C.A.C., O.T., S.J.K.).ORCID http://orcid.org/0000-0002-1564-1180
R CastellaniDepartment of Pathology (R.C.), University Homer Stryker M.D. School of Medicine, Kalamazoo, Michigan.ORCID http://orcid.org/0000-0003-0651-2333
S J KittnerNeurology (J.N.G., C.A.C., O.T., S.J.K.).ORCID http://orcid.org/0000-0002-8457-8744
D GandhiInterventional Neuroradiology (D.G.), University of Maryland School of Medicine, Baltimore, Maryland.ORCID http://orcid.org/0000-0001-6741-5970
P RaghavanFrom the Departments of Diagnostic Radiology and Nuclear Medicine (P.R., P.I.S., T.K., J.Z.) prashant.raghavan@gmail.com.ORCID http://orcid.org/0000-0001-6089-733X
Norwegian Womens Public Health Association · NOCentre de Recherche en Sciences et Technologies de l'Information et de la Communication · FROchsner Medical Center · USPRA Health Sciences · USUniversity of Maryland, Baltimore · USWestern Michigan University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeCarotid webs are intraluminal shelf-like filling defects at the carotid bulb with recently recognized implications in patients with recurrent ischemic stroke. We sought to determine whether carotid webs are an under-recognized cause of "cryptogenic" ischemic stroke and to estimate their prevalence in the general population. MATERIALS AND

methodsA retrospective review of neck CTA studies in young patients with cryptogenic stroke over the past 6 years (

resultsThe prevalence of carotid webs in the cryptogenic stroke population was 21.2% (95% CI, 8.9%-38.9%). Patients with symptomatic carotid webs had a mean age of 38.9 years (range, 30-48 years) and were mostly African American (86%) and women (86%). In contrast, only 1.6% (95% CI, 0%-8.5%) of patients in the control group demonstrated a web. Our findings demonstrate a statistically significant association between carotid webs and ischemic stroke (OR = 16.7; 95% CI, 2.78-320.3;

conclusionsCarotid webs exhibit a strong association with ischemic stroke, and their presence should be suspected in patients lacking other risk factors, particularly African American women.

Indexed as

AdolescentAdultBlack or African AmericanBrain IschemiaCarotid ArteriesCarotid Artery DiseasesCerebral AngiographyFemaleFunctional LateralityHumansMagnetic Resonance AngiographyMaleMiddle AgedNeckPrevalenceRetrospective Studies

Identifiers

PMID28495950
PMCPMC7959897
OpenAlexW2611977136

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.