Evidence map›Paper›PMID 28495945›Full record

ArticleAJNR. American journal of neuroradiology2017

Role of High-Resolution Dynamic Contrast-Enhanced MRI with Golden-Angle Radial Sparse Parallel Reconstruction to Identify the Normal Pituitary Gland in Patients with Macroadenomas.

R Sen, C Sen, J Pack, K T Block, J G Golfinos, V Prabhu, F Boada, O Gonen, D Kondziolka, G Fatterpekar

Abstract read
In one paragraph

Article in AJNR. American journal of neuroradiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

R SenFrom the New York University School of Medicine, NYU Langone Medical Center, New York, New York.ORCID http://orcid.org/0000-0002-1428-5575
C SenFrom the New York University School of Medicine, NYU Langone Medical Center, New York, New York.ORCID http://orcid.org/0000-0003-1603-2958
J PackFrom the New York University School of Medicine, NYU Langone Medical Center, New York, New York.ORCID http://orcid.org/0000-0003-3574-9217
K T BlockFrom the New York University School of Medicine, NYU Langone Medical Center, New York, New York.ORCID http://orcid.org/0000-0003-3426-965X
J G GolfinosFrom the New York University School of Medicine, NYU Langone Medical Center, New York, New York.ORCID http://orcid.org/0000-0003-4221-0180
V PrabhuFrom the New York University School of Medicine, NYU Langone Medical Center, New York, New York.ORCID http://orcid.org/0000-0002-8933-7392
F BoadaFrom the New York University School of Medicine, NYU Langone Medical Center, New York, New York.ORCID http://orcid.org/0000-0002-3289-9917
O GonenFrom the New York University School of Medicine, NYU Langone Medical Center, New York, New York.ORCID http://orcid.org/0000-0002-3148-2028
D KondziolkaFrom the New York University School of Medicine, NYU Langone Medical Center, New York, New York.ORCID http://orcid.org/0000-0001-8925-7344
G FatterpekarFrom the New York University School of Medicine, NYU Langone Medical Center, New York, New York. girish.fatterpekar@nyumc.org.ORCID http://orcid.org/0000-0002-4705-2030

Funding

TR&D 4: Revealing Microstructure: Biophysical modeling and validation for discovery and clinical careP41EB017183 · NIBIB · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Hersh Chandarana · 2014 to 2026
$19.3M
NIBIB NIH HHS P41 EB017183
6 · The paper itself

Abstract

background and purposePreoperative localization of the pituitary gland with imaging in patients with macroadenomas has been inadequately explored. The pituitary gland enhancing more avidly than a macroadenoma has been described in the literature. Taking advantage of this differential enhancement pattern, our aim was to evaluate the role of high-resolution dynamic MR imaging with golden-angle radial sparse parallel reconstruction in localizing the pituitary gland in patients undergoing trans-sphenoidal resection of a macroadenoma. MATERIALS AND

methodsA retrospective study was performed in 17 patients who underwent trans-sphenoidal surgery for pituitary macroadenoma. Radial volumetric interpolated brain examination sequences with golden-angle radial sparse parallel technique were obtained. Using an ROI-based method to obtain signal-time curves and permeability measures, 3 separate readers identified the normal pituitary gland distinct from the macroadenoma. The readers' localizations were then compared with the intraoperative location of the gland. Statistical analyses were performed to assess the interobserver agreement and correlation with operative findings.

resultsThe normal pituitary gland was found to have steeper enhancement-time curves as well as higher peak enhancement values compared with the macroadenoma (

conclusionsThis study confirms our ability to consistently and accurately identify the normal pituitary gland in patients with macroadenomas with the golden-angle radial sparse parallel technique with quantitative permeability measurements and enhancement-time curves.

Indexed as

AdenomaAdultAgedContrast MediaFemaleHumansMagnetic Resonance ImagingMaleMiddle AgedPituitary GlandPituitary NeoplasmsRetrospective StudiesContrast Media

Identifiers

PMID28495945
PMCPMC6080601

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.