Evidence map›Paper›PMID 28495904›Full record

ArticleThe British journal of ophthalmology2018

Assessing total retinal blood flow in diabetic retinopathy using multiplane en face Doppler optical coherence tomography.

Alex D Pechauer, Thomas S Hwang, Ahmed M Hagag, Liang Liu, Ou Tan, Xinbo Zhang, Maria Parker, David Huang, David J Wilson, Yali Jia

Open access · greenAbstract read
In one paragraph

Article in The British journal of ophthalmology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
0.2field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Rod photoreceptor activation and deactivation in early-stage diabetic eye disease.Documenta ophthalmologica. Advances in ophthalmology · 2023
    Article
  5. Article
  6. Article
  7. Article
  8. Variability of Retinal Oxygen Metrics in Healthy and Diabetic Subjects.Translational vision science & technology · 2021
    Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Maximum value projection produces betterBiomedical optics express · 2018
    Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Alex D PechauerCasey Eye Institute, Oregon Health & Science University, Portland, Oregon, USA.
Thomas S HwangCasey Eye Institute, Oregon Health & Science University, Portland, Oregon, USA.
Ahmed M HagagCasey Eye Institute, Oregon Health & Science University, Portland, Oregon, USA.
Liang LiuCasey Eye Institute, Oregon Health & Science University, Portland, Oregon, USA.
Ou TanCasey Eye Institute, Oregon Health & Science University, Portland, Oregon, USA.
Xinbo ZhangCasey Eye Institute, Oregon Health & Science University, Portland, Oregon, USA.
Maria ParkerCasey Eye Institute, Oregon Health & Science University, Portland, Oregon, USA.
David HuangCasey Eye Institute, Oregon Health & Science University, Portland, Oregon, USA.
David J WilsonCasey Eye Institute, Oregon Health & Science University, Portland, Oregon, USA.
Yali JiaCasey Eye Institute, Oregon Health & Science University, Portland, Oregon, USA.
Oregon Health & Science University · US

Funding

Proteomics CoreP30EY010572 · NEI · OREGON HEALTH & SCIENCE UNIVERSITY · PI Kate E Keller · 1995 to 2026
$19.4M
OCT Angiography for Neovascular Age-related Macular DegenerationR01EY024544 · NEI · OREGON HEALTH & SCIENCE UNIVERSITY · PI Steven T Bailey, Yali Jia · 2014 to 2026
$6.2M
Wide-field and projection-resolved optical coherence tomography angiography in diabetic retinopathyR01EY027833 · NEI · OREGON HEALTH & SCIENCE UNIVERSITY · PI HWANG, THOMAS, JIA, YALI · 2017 to 2020
$1.8M
Functional Optical Coherence Tomography-derived Biomarkers for Diabetic RetinopathyDP3DK104397 · NIDDK · OREGON HEALTH & SCIENCE UNIVERSITY · PI JIA, YALI, WILSON, DAVID J · 2014 to 2014
$1.0M
NEI NIH HHS P30 EY010572NEI NIH HHS R01 EY024544NEI NIH HHS R01 EY027833NIDDK NIH HHS DP3 DK104397
6 · The paper itself

Abstract

aimTo assess total retinal blood flow (TRBF) in diabetic retinopathy (DR) using multiplane

methodsA 70 kHz spectral-domain OCT system scanned a 2×2 mm area centred at the optic disc of the eyes with DR and healthy participants. The multiplane

resultsA total of 71 eyes from 71 participants were included. Ten eyes were excluded due to poor image quality. The within-visit repeatability of scans was 4.1% (coefficient of variation). There was no significant difference in the TRBF between the healthy (46.7±10.2 µL/min) and mild/moderate non-proliferative DR (44.9±12.6 µL/min) groups. The TRBF in severe non-proliferative DR (39.1±12.6 µL/min) and proliferative DR (28.9±8.85 µL/min) groups were significantly lower (

conclusionThe novel multiplane

Indexed as

AlgorithmsBlood Flow VelocityCross-Sectional StudiesDiabetic RetinopathyFemaleFollow-Up StudiesHealthy VolunteersHumansImaging, Three-DimensionalMaleMiddle AgedRegional Blood FlowRetinal VesselsTime FactorsTomography, Optical CoherenceDiabetic retinopathyimagingoptical coherence tomographyretinaretinal blood flow

Identifiers

PMID28495904
PMCPMC5800769
OpenAlexW2583621735

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.