Evidence map›Paper›PMID 28495386›Full record

ArticleBioorganic & medicinal chemistry2017

Development of molecular tools based on the dopamine D

Anne Stößel, Regine Brox, Nirupam Purkayastha, Harald Hübner, Carsten Hocke, Olaf Prante, Peter Gmeiner

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Bioorganic & medicinal chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Fluorescent ligands for dopamine DScientific reports · 2020
    Article
  3. Review
  4. The highly selective dopamine DNeuropharmacology · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Anne StößelDepartment of Medicinal Chemistry, Emil Fischer Center, Friedrich-Alexander University, Schuhstraβe 19, D-91052 Erlangen, Germany.
Regine BroxDepartment of Medicinal Chemistry, Emil Fischer Center, Friedrich-Alexander University, Schuhstraβe 19, D-91052 Erlangen, Germany.
Nirupam PurkayasthaDepartment of Medicinal Chemistry, Emil Fischer Center, Friedrich-Alexander University, Schuhstraβe 19, D-91052 Erlangen, Germany.
Harald HübnerDepartment of Medicinal Chemistry, Emil Fischer Center, Friedrich-Alexander University, Schuhstraβe 19, D-91052 Erlangen, Germany.
Carsten HockeDepartment of Nuclear Medicine, Ulmenweg 18, D-91054 Erlangen, Germany.
Olaf PranteDepartment of Nuclear Medicine, Ulmenweg 18, D-91054 Erlangen, Germany.
Peter GmeinerDepartment of Medicinal Chemistry, Emil Fischer Center, Friedrich-Alexander University, Schuhstraβe 19, D-91052 Erlangen, Germany. Electronic address: peter.gmeiner@fau.de.
Friedrich-Alexander-Universität Erlangen-Nürnberg · DE

Funding

Structure-based discovery of allosteric ligands for G Protein Coupled ReceptorsU19GM106990 · NIGMS · STANFORD UNIVERSITY · PI KOBILKA, BRIAN K · 2013 to 2017
$6.3M
NIGMS NIH HHS U19 GM106990
6 · The paper itself

Abstract

Dopamine D

Indexed as

AnimalsDisease Models, AnimalDose-Response Relationship, DrugHumansLigandsMiceMolecular StructurePositron-Emission TomographyPyrazolesPyridinesRatsReceptors, Dopamine D3Structure-Activity Relationship2-(4-(4-chlorophenyl)piperazin-1-ylmethyl)pyrazolo(1,5-a)-pyridineLigandsPyrazolesPyridinesReceptors, Dopamine D3AutoradiographyDopamine D(3) receptorDrug maintained behaviorFluorine-18Food maintained behaviorPositron emission tomography (PET)Selective D(3) antagonistSelf-administrationSubtype selectivity

Identifiers

PMID28495386
PMCPMC5512454
OpenAlexW2609711934

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.