Evidence map›Paper›PMID 28495022›Full record

ArticleComprehensive psychiatry2017

Delineating the joint hierarchical structure of clinical and personality disorders in an outpatient psychiatric sample.

Miriam K Forbes, Roman Kotov, Camilo J Ruggero, David Watson, Mark Zimmerman, Robert F Krueger

Abstract read
In one paragraph

Article in Comprehensive psychiatry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Validity and utility of Hierarchical Taxonomy of Psychopathology (HiTOP): III. Emotional dysfunction superspectrum.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2022
    Article
  8. Article
  9. Article
  10. Validity and utility of Hierarchical Taxonomy of Psychopathology (HiTOP): II. Externalizing superspectrum.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2021
    Article
  11. A detailed hierarchical model of psychopathology: From individual symptoms up to the general factor of psychopathology.Clinical psychological science : a journal of the Association for Psychological Science · 2021
    Article
  12. Annales medico-psychologiques · 2021
    Article
  13. Article
  14. Article
  15. Testing structural models of psychopathology at the genomic level.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2020
    Article
  16. Article
  17. Validity and utility of Hierarchical Taxonomy of Psychopathology (HiTOP): I. Psychosis superspectrum.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2020
    Article
  18. Article
  19. Article
  20. Personality Pathology and Schizophrenia.Schizophrenia bulletin · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Miriam K ForbesDepartments of Psychiatry and Psychology, University of Minnesota-Twin Cities Campus, 2450 Riverside Ave, Suite F227, Minneapolis, MN 55454, United States. Electronic address: mkforbes@umn.edu.
Roman KotovDepartment of Psychiatry, Stony Brook University, HSC, Level T-10, Room 060H, Stony Brook, NY 11794-8101, United States. Electronic address: roman.kotov@stonybrook.edu.
Camilo J RuggeroDepartment of Psychology, University of North Texas, 1155 Union Circle #311280, Denton, TX 76203, United States. Electronic address: Camilo.Ruggero@unt.edu.
David WatsonDepartment of Psychology, 118 Haggar Hall, University of Notre Dame, Notre Dame, IN 46556, United States. Electronic address: db.watson@nd.edu.
Mark Zimmerman146 West River St, Suite 11b, Providence, RI 02904, United States.. Electronic address: MZimmerman@lifespan.org.
Robert F KruegerDepartment of Psychology, N414 Elliott Hall, University of Minnesota-Twin Cities Campus, Minneapolis, MN 55455, United States. Electronic address: krueg038@umn.edu.

Funding

Comorbidity: Substance Use Disorders and Other Psychiatric ConditionsT32DA037183 · NIDA · UNIVERSITY OF MINNESOTA · PI Anna Zilverstand · 2014 to 2026
$3.2M
NIDA NIH HHS T32 DA037183
6 · The paper itself

Abstract

backgroundA large body of research has focused on identifying the optimal number of dimensions - or spectra - to model individual differences in psychopathology. Recently, it has become increasingly clear that ostensibly competing models with varying numbers of spectra can be synthesized in empirically derived hierarchical structures. METHODS AND MATERIALS: We examined the convergence between top-down (bass-ackwards or sequential principal components analysis) and bottom-up (hierarchical agglomerative cluster analysis) statistical methods for elucidating hierarchies to explicate the joint hierarchical structure of clinical and personality disorders. Analyses examined 24 clinical and personality disorders based on semi-structured clinical interviews in an outpatient psychiatric sample (n=2900).

resultsThe two methods of hierarchical analysis converged on a three-tier joint hierarchy of psychopathology. At the lowest tier, there were seven spectra - disinhibition, antagonism, core thought disorder, detachment, core internalizing, somatoform, and compulsivity - that emerged in both methods. These spectra were nested under the same three higher-order superspectra in both methods: externalizing, broad thought dysfunction, and broad internalizing. In turn, these three superspectra were nested under a single general psychopathology spectrum, which represented the top tier of the hierarchical structure.

conclusionsThe hierarchical structure mirrors and extends upon past research, with the inclusion of a novel compulsivity spectrum, and the finding that psychopathology is organized in three superordinate domains. This hierarchy can thus be used as a flexible and integrative framework to facilitate psychopathology research with varying levels of specificity (i.e., focusing on the optimal level of detailed information, rather than the optimal number of factors).

Indexed as

Models, PsychologicalAdultFemaleHumansMaleMental DisordersMood DisordersOutpatient Clinics, HospitalOutpatientsPersonalityPersonality DisordersProblem BehaviorPsychopathology

Identifiers

PMID28495022
PMCPMC5643220

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.