Evidence map›Paper›PMID 28495009›Full record

ArticleComputer methods and programs in biomedicine2017

A two-step convolutional neural network based computer-aided detection scheme for automatically segmenting adipose tissue volume depicting on CT images.

Yunzhi Wang, Yuchen Qiu, Theresa Thai, Kathleen Moore, Hong Liu, Bin Zheng

Abstract read
In one paragraph

Article in Computer methods and programs in biomedicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Precision or Paradox? AI-Driven Adiposity Imaging in Women With Overweight and Obesity: A Systematic Review and Meta-Analysis.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2026
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  12. Deep learning for abdominal adipose tissue segmentation with few labelled samples.International journal of computer assisted radiology and surgery · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yunzhi WangSchool of Electrical and Computer Engineering, University of Oklahoma, Norman, OK 73019, United States. Electronic address: yunzhi.wang-1@ou.edu.
Yuchen QiuSchool of Electrical and Computer Engineering, University of Oklahoma, Norman, OK 73019, United States.
Theresa ThaiHealth Science Center of University of Oklahoma, Oklahoma City, OK 73104, United States.
Kathleen MooreHealth Science Center of University of Oklahoma, Oklahoma City, OK 73104, United States.
Hong LiuSchool of Electrical and Computer Engineering, University of Oklahoma, Norman, OK 73019, United States.
Bin ZhengSchool of Electrical and Computer Engineering, University of Oklahoma, Norman, OK 73019, United States.

Funding

Increasing Cancer Detection Yield Using Breast MRI Screening ModalityR01CA197150 · NCI · UNIVERSITY OF OKLAHOMA · PI HOLLINGSWORTH, ALAN B., LIU, HONG · 2015 to 2019
$2.5M
EPA EP-D-15-016NCI NIH HHS R01 CA197150
6 · The paper itself

Abstract

Accurately assessment of adipose tissue volume inside a human body plays an important role in predicting disease or cancer risk, diagnosis and prognosis. In order to overcome limitation of using only one subjectively selected CT image slice to estimate size of fat areas, this study aims to develop and test a computer-aided detection (CAD) scheme based on deep learning technique to automatically segment subcutaneous fat areas (SFA) and visceral fat areas (VFA) depicting on volumetric CT images. A retrospectively collected CT image dataset was divided into two independent training and testing groups. The proposed CAD framework consisted of two steps with two convolution neural networks (CNNs) namely, Selection-CNN and Segmentation-CNN. The first CNN was trained using 2,240 CT slices to select abdominal CT slices depicting SFA and VFA. The second CNN was trained with 84,000pixel patches and applied to the selected CT slices to identify fat-related pixels and assign them into SFA and VFA classes. Comparing to the manual CT slice selection and fat pixel segmentation results, the accuracy of CT slice selection using the Selection-CNN yielded 95.8%, while the accuracy of fat pixel segmentation using the Segmentation-CNN was 96.8%. This study demonstrated the feasibility of applying a new deep learning based CAD scheme to automatically recognize abdominal section of human body from CT scans and segment SFA and VFA from volumetric CT data with high accuracy or agreement with the manual segmentation results.

Indexed as

Image Interpretation, Computer-AssistedNeural Networks, ComputerTomography, X-Ray ComputedAbdomenAbdominal FatHumansIntra-Abdominal FatSubcutaneous FatComputer-aided detection (CAD)Convolution neural network (CNN)Deep learningSegmentation of adipose tissueSubcutaneous fat area (SFA)Visceral fat area (VFA)

Identifiers

PMID28495009
PMCPMC5441239

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.