ReviewJournal of the American College of Cardiology2017
Extracorporeal Ultrafiltration for Fluid Overload in Heart Failure: Current Status and Prospects for Further Research.
Review in Journal of the American College of Cardiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04572867 (Efficacy of Aquapheresis in Patients Treated as Outpatients With Decompensated Heart Failure at a Veterans Hospital), which is not on this map. Cited by 56 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Efficacy of Aquapheresis in Patients Treated as Outpatients With Decompensated Heart Failure at a Veterans Hospital
Who cites it
56 citing papers in PubMed, 2 syntheses or guidelines pooled it, 121 citations in OpenAlex.
- Analysis of the usefulness and benefits of ultrafiltration in cardiorenal syndrome: A systematic review.ESC heart failure · 2025Pooled it
- Ultrafiltration for acute heart failure.The Cochrane database of systematic reviews · 2022Pooled it
- [Capacity Management During the Hospital-to-Home Transition Period for Patients With Chronic Heart Failure].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2026Trial
- Best Evidence Summary for Volume Management of Patients With Heart and Kidney Comorbidity.Nursing open · 2026Review
- Worsening versus advanced heart failure: Management and challenges.ESC heart failure · 2025Review
- Decongestion in heart failure: medical and device therapies.Nature reviews. Cardiology · 2025Review
- Heart Failure Readmission Prevention Strategies-A Comparative Review of Medications, Devices, and Other Interventions.Journal of clinical medicine · 2025Review
- A wearable belt for non-invasive monitoring of heart failure parameters.Sensing and Bio-Sensing Research · 2025Article
- Deep Dive into the Cardio-Pulmonary-Renal Interactions in Patients with Pulmonary Hypertension: Serum Creatinine Levels Even Within the Normal Range Related to Long-Term Survival.Anatolian journal of cardiology · 2025Article
- Advanced chronic kidney disease coexisting with heart failure: navigating patients' management.Clinical kidney journal · 2025Review
- The impact of preprocedural pulmonary artery systolic pressure on acute kidney injury related to transcatheter aortic valve replacement.Postepy w kardiologii interwencyjnej = Advances in interventional cardiology · 2025Article
- Dietary sodium intake restriction in patients with heart failure: an overview of systematic reviews.Heart failure reviews · 2025Review
- Diuretic resistance in cardiorenal syndrome: mechanisms, monitoring and phenotype-tailored management.Frontiers in cardiovascular medicine · 2025Review
- Rapid-onset postoperative acute kidney injury is associated with mortality in patients with postcardiotomy cardiogenic shock.Frontiers in cardiovascular medicine · 2025Article
- Mechanisms of Congestion in Acute Decompensated Heart Failure.Cardiorenal medicine · 2025Review
- The utility of urine sodium-guided diuresis during acute decompensated heart failure.Heart failure reviews · 2024Review
- From Hospital to Home: Evidence-Based Care for Worsening Heart Failure.JACC. Advances · 2024Review
- Phenotyping Refractory Cardiogenic Shock Patients Receiving Venous-Arterial Extracorporeal Membrane Oxygenation Using Machine Learning Algorithms.Reviews in cardiovascular medicine · 2024Article
- Development of a new miniaturized system for ultrafiltration.Heart failure reviews · 2024Review
- Congestion in Heart Failure: From the Secret of a Mummy to Today's Novel Diagnostic and Therapeutic Approaches: A Comprehensive Review.Journal of clinical medicine · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
18 authors at 18 institutions in 4 countries.
Funding
Abstract
More than 1 million heart failure hospitalizations occur annually, and congestion is the predominant cause. Rehospitalizations for recurrent congestion portend poor outcomes independently of age and renal function. Persistent congestion trumps serum creatinine increases in predicting adverse heart failure outcomes. No decongestive pharmacological therapy has reduced these harmful consequences. Simplified ultrafiltration devices permit fluid removal in lower-acuity hospital settings, but with conflicting results regarding safety and efficacy. Ultrafiltration performed at fixed rates after onset of therapy-induced increased serum creatinine was not superior to standard care and resulted in more complications. In contrast, compared with diuretic agents, some data suggest that adjustment of ultrafiltration rates to patients' vital signs and renal function may be associated with more effective decongestion and fewer heart failure events. Essential aspects of ultrafiltration remain poorly defined. Further research is urgently needed, given the burden of congestion and data suggesting sustained benefits of early and adjustable ultrafiltration.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.