Evidence map›Paper›PMID 28494970›Full record

ArticleBiophysical journal2017

Image-Based Measurement of H

Mark Jelcic, Balázs Enyedi, João B Xavier, Philipp Niethammer

Open access · bronzeAbstract readVideo-Audio Media
In one paragraph

Article in Biophysical journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 31 citations in OpenAlex.

  1. DHRS7 Integrates NADPbioRxiv : the preprint server for biology · 2025
    Article
  2. Article
  3. Coordinated NADPH oxidase/hydrogen peroxide functions regulate cutaneous sensory axon de- and regeneration.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. In Vivo Imaging with Genetically Encoded Redox Biosensors.International journal of molecular sciences · 2020
    Review
  9. Wound redox gradients revisited.Seminars in cell & developmental biology · 2018
    Review
  10. Article
  11. An automated quantitative image analysis pipeline ofJournal of biological methods · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Mark JelcicCell Biology Program, Memorial Sloan Kettering Cancer Center, New York, New York; Louis V. Gerstner, Jr. Graduate School of Biomedical Sciences, Memorial Sloan Kettering Cancer Center, New York, New York.
Balázs EnyediDepartment of Physiology, Faculty of Medicine, Semmelweis University, Budapest, Hungary.
João B XavierComputational and Systems Biology Program, Memorial Sloan Kettering Cancer Center, New York, New York. Electronic address: xavierj@mskcc.org.
Philipp NiethammerCell Biology Program, Memorial Sloan Kettering Cancer Center, New York, New York. Electronic address: niethamp@mskcc.org.
Memorial Sloan Kettering Cancer Center · USSemmelweis University · HU

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
Regulation of Wound Detection in Animal TissuesR01GM099970 · NIGMS · SLOAN-KETTERING INST CAN RESEARCH · PI NIETHAMMER, PHILIPP MICHAEL · 2012 to 2020
$3.2M
Engineering microbial social interactions: Towards new anti-biofilm therapiesDP2OD008440 · OD · SLOAN-KETTERING INST CAN RESEARCH · PI XAVIER, JOAO · 2011 to 2015
$2.9M
NCI NIH HHS P30 CA008748NIGMS NIH HHS R01 GM099970NIH HHS DP2 OD008440
6 · The paper itself

Abstract

Epithelial injury induces rapid recruitment of antimicrobial leukocytes to the wound site. In zebrafish larvae, activation of the epithelial NADPH oxidase Duox at the wound margin is required early during this response. Before injury, leukocytes are near the vascular region, that is, ∼100-300 μm away from the injury site. How Duox establishes long-range signaling to leukocytes is unclear. We conceived that extracellular hydrogen peroxide (H

Indexed as

Microscopy, FluorescenceAnimal FinsAnimalsAnimals, Genetically ModifiedAntioxidantsDiffusionHydrogen PeroxideImage Processing, Computer-AssistedKineticsLarvaModels, AnimalMolecular ImagingPeroxiredoxinsTailThioredoxinsZebrafishAntioxidantsHydrogen PeroxidePeroxiredoxinsThioredoxins

Identifiers

PMID28494970
PMCPMC5425381
OpenAlexW2613273453

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.