Evidence map›Paper›PMID 28494942›Full record

ArticleStem cell reports2017

RNA Polymerase III Subunit POLR3G Regulates Specific Subsets of PolyA

Riikka J Lund, Nelly Rahkonen, Maia Malonzo, Leni Kauko, Maheswara Reddy Emani, Virpi Kivinen, Elisa Närvä, Esko Kemppainen, Asta Laiho, Heli Skottman and 5 more

Open access · goldAbstract read
In one paragraph

Article in Stem cell reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. The homeostatic regulation of ribosome biogenesis.Seminars in cell & developmental biology · 2023
    Review
  8. RNA Polymerases I and III in development and disease.Seminars in cell & developmental biology · 2023
    Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 7 institutions in 2 countries.

Riikka J LundTurku Centre for Biotechnology, University of Turku and Åbo Akademi University, Turku 20520, Finland. Electronic address: riikka.lund@utu.fi.
Nelly RahkonenTurku Centre for Biotechnology, University of Turku and Åbo Akademi University, Turku 20520, Finland.
Maia MalonzoDepartment of Computer Science, Aalto University, Espoo 02150, Finland.
Leni KaukoTurku Centre for Biotechnology, University of Turku and Åbo Akademi University, Turku 20520, Finland.
Maheswara Reddy EmaniTurku Centre for Biotechnology, University of Turku and Åbo Akademi University, Turku 20520, Finland.
Virpi KivinenFaculty of Medicine and Life Sciences, BioMediTech, University of Tampere, Tampere 33014, Finland.
Elisa NärväTurku Centre for Biotechnology, University of Turku and Åbo Akademi University, Turku 20520, Finland.
Esko KemppainenTurku Centre for Biotechnology, University of Turku and Åbo Akademi University, Turku 20520, Finland.
Asta LaihoTurku Centre for Biotechnology, University of Turku and Åbo Akademi University, Turku 20520, Finland.
Heli SkottmanFaculty of Medicine and Life Sciences, BioMediTech, University of Tampere, Tampere 33014, Finland.
Outi HovattaDepartment CLINTEC, Karolinska Institutet, Karolinska University Hospital Huddinge, Stockholm 171 77, Sweden.
Omid RasoolTurku Centre for Biotechnology, University of Turku and Åbo Akademi University, Turku 20520, Finland.
Matti NykterTurku Centre for Biotechnology, University of Turku and Åbo Akademi University, Turku 20520, Finland; Faculty of Medicine and Life Sciences, BioMediTech, University of Tampere, Tampere 33014, Finland.
Harri LähdesmäkiTurku Centre for Biotechnology, University of Turku and Åbo Akademi University, Turku 20520, Finland; Department of Computer Science, Aalto University, Espoo 02150, Finland.
Riitta LahesmaaTurku Centre for Biotechnology, University of Turku and Åbo Akademi University, Turku 20520, Finland.
University of Turku · FIÅbo Akademi University · FIAalto University · FIKarolinska Institutet · SETampere University · FITampere University · FITurku Centre for Biotechnology · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

POLR3G is expressed at high levels in human pluripotent stem cells (hPSCs) and is required for maintenance of stem cell state through mechanisms not known in detail. To explore how POLR3G regulates stem cell state, we carried out deep-sequencing analysis of polyA

Indexed as

PolyadenylationRNA SplicingTranscriptomeCell LineDNA Polymerase gammaHuman Embryonic Stem CellsHumansInduced Pluripotent Stem CellsRNA Polymerase IIIRNA, Small UntranslatedDNA Polymerase gammaPOLG protein, humanPOLR3G protein, humanRNA Polymerase IIIRNA, Small Untranslatedhuman embryonic stem cellmitochondriapluripotencypolyA(+) RNApolymerase IIIsmallRNAsplicingtranscriptome

Identifiers

PMID28494942
PMCPMC5425787
OpenAlexW2613404718

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.