ReviewGut and liver2018
Diverticular Disease: An Update on Pathogenesis and Management.
Review in Gut and liver, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 68 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
68 citing papers in PubMed, 5 syntheses or guidelines pooled it, 170 citations in OpenAlex.
- Diverticulitis-Associated Mesenteric Venous Thrombophlebitis: A Case Report and Systematic Review of Diagnosis, Management, and Outcomes.The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi · 2026Pooled it
- Are Nuts Safe in Diverticulosis? A Mixed-Methods Systematic Review of Available Evidence.Nutrients · 2025Pooled it
- Do Colonic Mucosal Tumor Necrosis Factor Alpha Levels Play a Role in Diverticular Disease? A Systematic Review and Meta-Analysis.International journal of molecular sciences · 2023Pooled it
- Gut Microbiota Association with Diverticular Disease Pathogenesis and Progression: A Systematic Review.Digestive diseases and sciences · 2023Pooled it
- Non-steroidal anti-inflammatory drugs and acetylsalicylic acid increase the risk of complications of diverticular disease: a meta-analysis of case-control and cohort studies.International journal of colorectal disease · 2022Pooled it
- Effects of Burdock tea on recurrence of colonic diverticulitis and diverticular bleeding: An open-labelled randomized clinical trial.Scientific reports · 2019Trial
- Ethnic Disparities in Colonic Diverticulosis Between Arab and Jewish Patients: A Large Nationwide Cohort Study.Journal of immigrant and minority health · 2026Article
- A focus of therapeutic strategies in acute diverticulitis with distant free air: a systematic review.Updates in surgery · 2025Review
- Trends in diverticular disease mortality among United States adults (1999-2020) by gender, race, and geographic region.World journal of gastrointestinal pharmacology and therapeutics · 2025Article
- Bowel Transit Time May Be Accelerated in Colonic Diverticulosis Independent of Mucosal Serotonin Signaling.Journal of clinical medicine · 2025Article
- Coffee Consumption and Risk of Incident Gastrointestinal Disease: A Large Prospective Cohort Study.Food science & nutrition · 2025Article
- Article
- Impact of Dementia on Patients Admitted With Complicated Diverticular Disease: A U.S. Nationwide Analysis.Cureus · 2025Article
- Identification of core gene-gut microbiome associations in diverticulitis patients through a two-sample mendelian randomization and bioinformatics-based investigation.Global medical genetics · 2025Article
- The Emerging Role of the Microbiota and Antibiotics in Diverticulitis Treatment.Clinics in colon and rectal surgery · 2025Review
- Safety and efficacy of faecal microbiota transplantation in patients with acute uncomplicated diverticulitis: study protocol for a randomised placebo-controlled trial.Therapeutic advances in gastroenterology · 2025Article
- A unique case of gastrointestinal bleeding with splenomegaly.SAGE open medical case reports · 2025Article
- Triple Colonic Fistula Due to Complicated Diverticular Disease and Its Surgical Management.Cureus · 2024Article
- Acute diverticulitis requiring hospitalization according to regional discrepancies in France between 2013 and 2022: a nationwide study.Langenbeck's archives of surgery · 2024Article
- Recent updates on classification and unsolved issues of diverticular disease: a narrative review.Journal of Yeungnam medical science · 2024Article
8 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Diverticular disease is one of the most common conditions in the Western world and one of the most common findings identified at colonoscopy. Recently, there has been a significant paradigm shift in our understanding of diverticular disease and its management. The pathogenesis of diverticular disease is thought to be multifactorial and include both environmental and genetic factors in addition to the historically accepted etiology of dietary fiber deficiency. Symptomatic uncomplicated diverticular disease (SUDD) is currently considered a type of chronic diverticulosis that is perhaps akin to irritable bowel syndrome. Mesalamine, rifaximin and probiotics may achieve symptomatic relief in some patients with SUDD, although their role(s) in preventing complications remain unclear. Antibiotic use for acute diverticulitis and elective prophylactic resection surgery are considered more individualized treatment modalities that take into account the clinical status, comorbidities and lifestyle of the patient. Our understanding of the pathogenesis of diverticular disease continues to evolve and is likely to be diverse and multifactorial. Paradigm shifts in several areas of the pathogenesis and management of diverticular disease are explored in this review.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.