Evidence map›Paper›PMID 28494342›Full record

ArticleVirology2017

Genome sequence variation among isolates of monkey B virus (Macacine alphaherpesvirus 1) from captive macaques.

R Eberle, L K Maxwell, S Nicholson, D Black, L Jones-Engel

Abstract read
In one paragraph

Article in Virology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. A narrative review of monkey B virus (Clinical and experimental vaccine research · 2025
    Review
  5. Review
  6. Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

R EberleDepartment of Veterinary Pathobiology, Center for Veterinary Health Sciences, Oklahoma State University, Stillwater, OK, USA. Electronic address: r.eberle@okstate.edu.
L K MaxwellDepartment of Physiological Sciences, Center for Veterinary Health Sciences, Oklahoma State University, Stillwater, OK, USA.
S NicholsonDepartment of Biochemistry and Molecular Biology, College of Agriculture Sciences and Natural Resources, Oklahoma State University, Stillwater, OK, USA.
D BlackDepartment of Veterinary Pathobiology, Center for Veterinary Health Sciences, Oklahoma State University, Stillwater, OK, USA.
L Jones-EngelDepartment of Anthropology, University of Washington, Seattle, WA, USA.

Funding

ZFC3H1 Regulation of Host Defense and Influenza A Virus PathogenesisP20GM103648 · NIGMS · OKLAHOMA STATE UNIVERSITY STILLWATER · PI CHENG, YONG · 2013 to 2022
$22.3M
Baboon Research Resource ProgramP40OD010988 · OD · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI BANKS, RON E · 2012 to 2018
$9.0M
Improved Treatment for Zoonotic BV InfectionsR24OD022013 · OD · OKLAHOMA STATE UNIVERSITY STILLWATER · PI MAXWELL, LARA K. · 2016 to 2019
$1.0M
NIGMS NIH HHS P20 GM103648NIH HHS P40 OD010988NIH HHS R24 OD022013
6 · The paper itself

Abstract

Complete genome sequences of 19 strains of monkey B virus (Macacine alphaherpesvirus 1; BV) isolated from several macaque species were determined. A low level of sequence variation was present among BV isolates from rhesus macaques. Most variation among BV strains isolated from rhesus macaques was located in regions of repetitive or quasi-repetitive sequence. Variation in coding sequences (polypeptides and miRNAs) was minor compared to regions of non-coding sequences. Non-coding sequences in the long and short repeat regions of the genome did however exhibit islands of conserved sequence. Oral and genital isolates from a single monkey were identical in sequence and varied only in the number of iterations of repeat units in several areas of repeats. Sequence variation between BV isolates from different macaque species (different BV genotypes) was much greater and was spread across the entire genome, confirming the existence of different genotypes of BV in different macaque species.

Indexed as

Genetic VariationGenome, ViralAnimalsGenotypeHerpes SimplexMacaca mulattaMonkey DiseasesPhylogenySimplexvirusGenome sequenceGenotypeMacacine alphaherpesvirus 1MacaqueMonkey B virus

Identifiers

PMID28494342
PMCPMC5535784

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.