ReviewCell host & microbe2017
Microbial Vertical Transmission during Human Pregnancy.
Review in Cell host & microbe, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 215 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
215 citing papers in PubMed, 3 syntheses or guidelines pooled it, 382 citations in OpenAlex.
- Prevalence of Viruses in Odontogenic Cysts and Tumours:Sultan Qaboos University medical journal · 2025Pooled it
- Pregnancy and COVID-19: high or low risk of vertical transmission.Clinical and experimental medicine · 2023Pooled it
- Vertical Transmission of Severe Acute Respiratory Syndrome Coronavirus 2: A Systematic Review.American journal of perinatology · 2020Pooled it
- Article
- Placental crises: disruptive selection and maternal under-investment as the foundations of mammalian placental evolution and dysfunction.Biological reviews of the Cambridge Philosophical Society · 2026Review
- HSV, HIV, and Pregnancy: Epidemiology, Viral Interactions, Management, and Prevention.Current HIV/AIDS reports · 2026Review
- Fetal and neonatal demise in zoonotic diseases: pathology and pathogenesis.Infection and immunity · 2026Review
- Congenital Cytomegalovirus Infection in Pregnancy: Challenges in Early Diagnosis, Reinfection, and Secondary Prevention.Viruses · 2026Review
- Establishment of In OvoAnimals : an open access journal from MDPI · 2026Article
- Viromic profiling of amniotic fluid reveals distinct viral communities associated with maternal health status.BMC pregnancy and childbirth · 2026Article
- Review
- First-year dynamics of the plasma virome and cytokine profile in infants born to mothers with syphilis.Journal of translational medicine · 2026Article
- A novel anti-Microbiology spectrum · 2026Article
- Editorial: Infectious diseases in maternal-fetal interface: role of immune system to combat this pathology and avoid or minimize a possible vertical transmission.Frontiers in immunology · 2026Article
- Comparative analysis of placental transmission mechanisms for Dengue and Zika viruses: outcomes and future directions.Frontiers in immunology · 2026Review
- Neonatal varicella complicated by Staphylococcus aureus lung abscess in a preterm infant: a case report.Frontiers in pediatrics · 2026Article
- COVID-19 vaccination and miscarriage risk: RNA-seq and bioinformatics analysis at the maternal-foetal interface.Journal of global health · 2025Article
- Phage therapy and its role in cancer treatment and control.Folia microbiologica · 2025Review
- Mechanisms of bacterial host-to-host transmission.Microbiology and molecular biology reviews : MMBR · 2025Review
- Differential susceptibility of human placental trophoblasts to Trypanosoma cruzi infection.Parasitology research · 2025Article
155 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 1 country.
Funding
Abstract
Congenital infections with pathogens such as Zika virus, Toxoplasma gondii, Listeria monocytogenes, Treponema pallidium, parvovirus, HIV, varicella zoster virus, Rubella, Cytomegalovirus, and Herpesviruses are a major cause of morbidity and mortality worldwide. Despite the devastating impact of microbial infections on the developing fetus, relatively little is known about how pathogens associated with congenital disease breach the placental barrier to transit vertically during human pregnancy. In this Review, we focus on transplacental transmission of pathogens during human gestation. We introduce the structure of the human placenta and describe the innate mechanisms by which the placenta restricts microbial access to the intrauterine compartment. Based on current knowledge, we also discuss the potential pathways employed by microorganisms to overcome the placental barrier and prospects for the future.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.