Evidence map›Paper›PMID 28494088›Full record

SynthesisThe Cochrane database of systematic reviews2017

Peripheral nerve blocks for hip fractures.

Joanne Guay, Martyn J Parker, Richard Griffiths, Sandra Kopp

4 registry-linked trialsAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in The Cochrane database of systematic reviews, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 4 registered trials, which are not on this map. Cited by 72 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
72citing papers in PubMed, 8 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04882384 nacompletednot on this mapstarted 2021, after this paper: background citation

Pericapsular Nerve Group Blocks for Hip Fractures in the Emergency Department: A Prospective, Observational, Feasibility Study

TypeinterventionalSponsorJacobi Medical CenterRan2021 to 2022Enrolled10ConditionsHip Fractures, Pain, AcuteArmsPericapsular Nerve Group Block
NCT04914988 completednot on this mapstarted 2018, after this paper: background citation

Pain Management in Geriatric Hip Fracture Patients With Ultrasound-guided Continuous Fascia Iliaca Compartment Block

Typeobservational_patient_registrySponsorMahidol UniversityRan2018 to 2019Enrolled20ConditionsHip Fractures, Acute Pain Due to Trauma
NCT05056675 nacompletednot on this mapstarted 2022, after this paper: background citation

The PENG Block in Elective Hip Surgery and Its Effect on Postoperative Pain and Length of Stay: A Multidisciplinary Prospective Randomized Double-blind Controlled Trial.

TypeinterventionalSponsorHôpital FribourgeoisRan2022 to 2023Enrolled151ConditionsPain, PostoperativeArmsPENG block, Placebo
NCT07073209 narecruitingnot on this mapstarted 2025, after this paper: background citation

PENG vs Femoral Block for Hip Fracture, A Pragmatic Cluster-Randomized Study

TypeinterventionalSponsorWeill Medical College of Cornell UniversityRan2025 to 2027Enrolled352ConditionsHip FracturesArmsPENG Block Administration, Femoral Block Administration, Bupivacaine , epinephrine Dexamethasone
3 · Its place in the literature

Who cites it

72 citing papers in PubMed, 8 syntheses or guidelines pooled it.

  1. Pooled it
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  3. Peripheral nerve blocks for hip fractures in adults.The Cochrane database of systematic reviews · 2020
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  20. Peripheral nerve blocks for hip fracture surgeries: a bibliometric and visual analysis.International journal of surgery (London, England) · 2025
    Review

12 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Joanne GuayDepartment of Anesthesiology, Faculty of Medicine, University of Sherbrooke, Sherbrooke, Quebec, Canada.
Martyn J ParkerDepartment of Orthopaedics, Peterborough and Stamford Hospitals NHS Foundation Trust, Peterborough City Hospital, CBU PO Box 211, Bretton Gate, Peterborough, Cambridgeshire, UK, PE3 9GZ.
Richard GriffithsDepartment of Anaesthesia, Peterborough and Stamford Hospitals NHS Foundation Trust, Edith Cavell Hospital, Bretton Gate, Peterborough, Cambridgeshire, UK, PE26 2UA.
Sandra KoppDepartment of Anesthesiology and Perioperative Medicine, Mayo Clinic College of Medicine, 200 1st St SW, Rochester, MN, USA, 55901.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundVarious nerve blocks with local anaesthetic agents have been used to reduce pain after hip fracture and subsequent surgery. This review was published originally in 1999 and was updated in 2001, 2002, 2009 and 2017.

objectivesThis review focuses on the use of peripheral nerves blocks as preoperative analgesia, as postoperative analgesia or as a supplement to general anaesthesia for hip fracture surgery. We undertook the update to look for new studies and to update the methods to reflect Cochrane standards. SEARCH

methodsFor the updated review, we searched the following databases: the Cochrane Central Register of Controlled Trials (CENTRAL; 2016, Issue 8), MEDLINE (Ovid SP, 1966 to August week 1 2016), Embase (Ovid SP, 1988 to 2016 August week 1) and the Cumulative Index to Nursing and Allied Health Literature (CINAHL) (EBSCO, 1982 to August week 1 2016), as well as trial registers and reference lists of relevant articles. SELECTION CRITERIA: We included randomized controlled trials (RCTs) involving use of nerve blocks as part of the care provided for adults aged 16 years and older with hip fracture. DATA COLLECTION AND ANALYSIS: Two review authors independently assessed new trials for inclusion, determined trial quality using the Cochrane tool and extracted data. When appropriate, we pooled results of outcome measures. We rated the quality of evidence according to the GRADE Working Group approach. MAIN

resultsWe included 31 trials (1760 participants; 897 randomized to peripheral nerve blocks and 863 to no regional blockade). Results of eight trials with 373 participants show that peripheral nerve blocks reduced pain on movement within 30 minutes of block placement (standardized mean difference (SMD) -1.41, 95% confidence interval (CI) -2.14 to -0.67; equivalent to -3.4 on a scale from 0 to 10; I AUTHORS'

conclusionsHigh-quality evidence shows that regional blockade reduces pain on movement within 30 minutes after block placement. Moderate-quality evidence shows reduced risk for pneumonia, decreased time to first mobilization and cost reduction of the analgesic regimen (single shot blocks).

Indexed as

Pain ManagementAgedAged, 80 and overAnesthetics, LocalConfusionFemaleHip FracturesHumansMaleMovementMyocardial InfarctionNerve BlockPain MeasurementPeripheral NervesPneumoniaPostoperative PainAnesthetics, Local

Identifiers

PMID28494088
PMCPMC6481480

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.