ArticlePLoS genetics2017
Amplifying recombination genome-wide and reshaping crossover landscapes in Brassicas.
Article in PLoS genetics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed, 50 citations in OpenAlex.
- Chromosomal collinearity drives meiotic instability in Brassica autoallopolyploid.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026Article
- Substantial non-homologous recombination and structural variation results from Brassica AABC and CCAB hybrid meiosis.The Plant journal : for cell and molecular biology · 2025Article
- The regulatory mechanisms controlling meiotic cross-over patterning in plants.Biochemical Society transactions · 2025Review
- Genomic Divergence Shaped the Genetic Regulation of Meiotic Homologous Recombination in Brassica Allopolyploids.Molecular biology and evolution · 2025Article
- Identification of quantitative trait loci (QTLs) for key cheese making phenotypes in the blue-cheese mold Penicillium roqueforti.PLoS genetics · 2025Article
- Contribution of crossing over to genetic variance in maize and wheat populations.The plant genome · 2025Article
- Unambiguous chromosome identification reveals the factors impacting irregular chromosome behaviors in allotriploid AAC Brassica.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2024Article
- Alternating between even and odd ploidy levels switches on and off the recombination control, even near the centromeres.The Plant cell · 2024Article
- Meiotic Behaviors of Allotetraploid Citrus Drive the Interspecific Recombination Landscape, the Genetic Structures, and Traits Inheritance in Tetrazyg Progenies Aiming to Select New Rootstocks.Plants (Basel, Switzerland) · 2023Article
- Dissecting the Meiotic Recombination Patterns in aInternational journal of molecular sciences · 2023Article
- If it ain't broke, don't fix it: evaluating the effect of increased recombination on response to selection for wheat breeding.G3 (Bethesda, Md.) · 2022Article
- Advances and Perspectives for Polyploidy Breeding in Orchids.Plants (Basel, Switzerland) · 2022Review
- Review
- Pentaploidization Enriches the Genetic Diversity of Wheat by Enhancing the Recombination of AB Genomes.Frontiers in plant science · 2022Article
- Modelling of gene loss propensity in the pangenomes of three Brassica species suggests different mechanisms between polyploids and diploids.Plant biotechnology journal · 2021Article
- Meiosis in crops: from genes to genomes.Journal of experimental botany · 2021Review
- Review
- A Modified Meiotic Recombination inBiology · 2021Article
- Enhancing backcross programs through increased recombination.Genetics, selection, evolution : GSE · 2021Article
- Rewiring Meiosis for Crop Improvement.Frontiers in plant science · 2021Review
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Authors and funding
16 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Meiotic recombination by crossovers (COs) is tightly regulated, limiting its key role in producing genetic diversity. However, while COs are usually restricted in number and not homogenously distributed along chromosomes, we show here how to disrupt these rules in Brassica species by using allotriploid hybrids (AAC, 2n = 3x = 29), resulting from the cross between the allotetraploid rapeseed (B. napus, AACC, 2n = 4x = 38) and one of its diploid progenitors (B. rapa, AA, 2n = 2x = 20). We produced mapping populations from different genotypes of both diploid AA and triploid AAC hybrids, used as female and/or as male. Each population revealed nearly 3,000 COs that we studied with SNP markers well distributed along the A genome (on average 1 SNP per 1.25 Mbp). Compared to the case of diploids, allotriploid hybrids showed 1.7 to 3.4 times more overall COs depending on the sex of meiosis and the genetic background. Most surprisingly, we found that such a rise was always associated with (i) dramatic changes in the shape of recombination landscapes and (ii) a strong decrease of CO interference. Hybrids carrying an additional C genome exhibited COs all along the A chromosomes, even in the vicinity of centromeres that are deprived of COs in diploids as well as in most studied species. Moreover, in male allotriploid hybrids we found that Class I COs are mostly responsible for the changes of CO rates, landscapes and interference. These results offer the opportunity for geneticists and plant breeders to dramatically enhance the generation of diversity in Brassica species by disrupting the linkage drag coming from limits on number and distribution of COs.
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