Evidence map›Paper›PMID 28493868›Full record

ArticlePloS one2017

Vertical ground reaction force marker for Parkinson's disease.

Md Nafiul Alam, Amanmeet Garg, Tamanna Tabassum Khan Munia, Reza Fazel-Rezai, Kouhyar Tavakolian

Abstract read
In one paragraph

Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  10. Wearable fall risk assessment by discriminating recessive weak foot individual.Journal of neuroengineering and rehabilitation · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Md Nafiul AlamDepartment of Electrical Engineering, University of North Dakota, Grand Forks, North Dakota, United States of America.ORCID http://orcid.org/0000-0003-3145-901X
Amanmeet GargSchool of Engineering Science, Simon Fraser University, Burnaby, British Columbia, Canada.
Tamanna Tabassum Khan MuniaDepartment of Electrical Engineering, University of North Dakota, Grand Forks, North Dakota, United States of America.
Reza Fazel-RezaiDepartment of Electrical Engineering, University of North Dakota, Grand Forks, North Dakota, United States of America.
Kouhyar TavakolianSchool of Engineering Science, Simon Fraser University, Burnaby, British Columbia, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Parkinson's disease (PD) patients regularly exhibit abnormal gait patterns. Automated differentiation of abnormal gait from normal gait can serve as a potential tool for early diagnosis as well as monitoring the effect of PD treatment. The aim of current study is to differentiate PD patients from healthy controls, on the basis of features derived from plantar vertical ground reaction force (VGRF) data during walking at normal pace. The current work presents a comprehensive study highlighting the efficacy of different machine learning classifiers towards devising an accurate prediction system. Selection of meaningful feature based on sequential forward feature selection, the swing time, stride time variability, and center of pressure features facilitated successful classification of control and PD gaits. Support Vector Machine (SVM), K-nearest neighbor (KNN), random forest, and decision trees classifiers were used to build the prediction model. We found that SVM with cubic kernel outperformed other classifiers with an accuracy of 93.6%, the sensitivity of 93.1%, and specificity of 94.1%. In comparison to other studies, utilizing same dataset, our designed prediction system improved the classification performance by approximately 10%. The results of the current study underscore the ability of the VGRF data obtained non-invasively from wearable devices, in combination with a SVM classifier trained on meticulously selected features, as a tool for diagnosis of PD and monitoring effectiveness of therapy post pathology.

Indexed as

AgedAged, 80 and overFemaleGaitHealthy VolunteersHumansMaleParkinson DiseaseSupport Vector MachineWalking

Identifiers

PMID28493868
PMCPMC5426596

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.