Evidence map›Paper›PMID 28493556›Full record

Trial reportAlcoholism, clinical and experimental research2017

Association of Anticipated and Laboratory-Derived Alcohol Stimulation, Sedation, and Reward.

Daniel J Fridberg, Sandra Y Rueger, Patrick Smith, Andrea C King

Abstract readClinical Trial
In one paragraph

Trial report in Alcoholism, clinical and experimental research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Trial
  2. The neurobiological markers of acute alcohol's subjective effects in humans.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2022
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  3. Trial
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  9. Sleep and circadian differences between light and heavy adult alcohol drinkers.Alcoholism, clinical and experimental research · 2022
    Article
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  12. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Daniel J FridbergDepartment of Psychiatry & Behavioral Neuroscience , The University of Chicago, Chicago, Illinois.ORCID http://orcid.org/0000-0003-3451-1418
Sandra Y RuegerDepartment of Psychiatry & Behavioral Neuroscience , The University of Chicago, Chicago, Illinois.
Patrick SmithDepartment of Psychiatry & Behavioral Neuroscience , The University of Chicago, Chicago, Illinois.
Andrea C KingDepartment of Psychiatry & Behavioral Neuroscience , The University of Chicago, Chicago, Illinois.

Funding

Alcohol Stimulation and Sedation in Binge Drinkers - Renewal 01R01AA013746 · NIAAA · UNIVERSITY OF CHICAGO · PI DANIEL J FRIDBERG, ANDREA C KING · 2003 to 2026
$11.6M
NIAAA NIH HHS R01 AA013746
6 · The paper itself

Abstract

backgroundLaboratory alcohol challenges are the "gold standard" for obtaining accurate measurements of subjective alcohol stimulation, sedation, and reward. However, these approaches are time and resource intensive. This study examined the extent to which self-reported anticipated alcohol stimulation, sedation, and reward corresponded with those same responses measured with the Biphasic Alcohol Effects Scale (BAES), Brief-BAES (B-BAES), and Drug Effects Questionnaire (DEQ) during a controlled laboratory alcohol challenge.

methodsParticipants were 106 light-to-heavy social drinkers (58.5% male; mean ± SD age = 35.8 ± 3.2 years) who completed the Anticipated BAES and DEQ, as well as laboratory-derived versions of these scales 30 and 60 minutes after consuming placebo and 0.8 g/kg alcohol on separate days as part of laboratory sessions in the Chicago Social Drinking Project.

resultsAnticipated BAES/B-BAES and Anticipated DEQ alcohol effects were strong predictors of their corresponding laboratory-derived responses during both the rising limb and at peak breath alcohol concentrations. Effects were significant even when accounting for age, sex, past-month heavy drinking frequency, and laboratory session order (placebo or alcohol first).

conclusionsThis study provides strong preliminary support for measuring anticipated alcohol effects with the Anticipated BAES/B-BAES and Anticipated DEQ as a proxy of subjective responses experienced during a controlled laboratory alcohol challenge. The findings lend support for these measures as viable alternatives to other anticipatory scales when laboratory-derived alcohol response measurement is not feasible.

Indexed as

Hypnotics and SedativesPsychometricsRewardStimulation, ChemicalAdultAlcohol DrinkingFemaleHumansMaleHypnotics and SedativesAlcohol ExpectanciesAnticipatedBiphasic Alcohol Effects ScaleDrug Effects QuestionnaireSubjective Alcohol Response

Identifiers

PMID28493556
PMCPMC5509338

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.