ArticleAngewandte Chemie (International ed. in English)2017
Strong Short-Range Cooperativity in Hydrogen-Bond Chains.
Article in Angewandte Chemie (International ed. in English), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- Carbohydrate Physicochemical Properties: The Innate Hydrogen Bond Donating Capacities of α-Glucoside and α-Galactoside Alcohol Groups.Angewandte Chemie (International ed. in English) · 2026Article
- Beyond Deshielding: NMR Evidence of Shielding in Hydridic and Protonic Hydrogen Bonds.Journal of chemical theory and computation · 2025Article
- Modeling Complex Proton Transport PhenomenaExploring the Limits of Fine-Tuning and Transferability of Foundational Machine-Learned Force Fields.The journal of physical chemistry. C, Nanomaterials and interfaces · 2025Article
- Unveiling Repulsion in Intramolecular H-Bonded Systems.Journal of the American Chemical Society · 2025Article
- Striking Impact of Solvent Polarity on the Strength of Hydrogen-Bonded Complexes: A Nexus Between Theory and Experiment.Angewandte Chemie (International ed. in English) · 2025Article
- Substituent Effects on Cooperativity in Three-Component H-Bond Networks Involving Phenol-Phenol Interactions.Journal of the American Chemical Society · 2025Article
- Negative cooperativity in the formation of H-bond networks involving primary anilines.Chemical science · 2024Article
- Coexistence of Cationic and Anionic Phosphate Moieties in Solids: Unusual but Not Impossible.The journal of physical chemistry letters · 2023Article
- Proton transfer reactions: From photochemistry to biochemistry and bioenergetics.BBA advances · 2023Article
- Quantitative Measurement of Cooperativity in H-Bonded Networks.Journal of the American Chemical Society · 2022Article
- Dissecting Solvent Effects on Hydrogen Bonding.Angewandte Chemie (International ed. in English) · 2022Article
- Halogen bonding organocatalysis enhanced through intramolecular hydrogen bonds.Chemical communications (Cambridge, England) · 2022Article
- Quantifying Through-Space Substituent Effects.Angewandte Chemie (International ed. in English) · 2020Article
- Reconciling Electrostatic and n→π* Orbital Contributions in Carbonyl Interactions.Angewandte Chemie (International ed. in English) · 2020Article
- Influence of intramolecular secondary sphere hydrogen-bonding interactions on cytochromeChemical science · 2019Article
- Synthetic Fe/Cu Complexes: Toward Understanding Heme-Copper Oxidase Structure and Function.Chemical reviews · 2018Review
- Polarisation effects on the solvation properties of alcohols.Chemical science · 2018Article
- Strong Short-Range Cooperativity in Hydrogen-Bond Chains.Angewandte Chemie (International ed. in English) · 2017Article
- Hydrogen bond design principles.Wiley interdisciplinary reviews. Computational molecular scienceArticle
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Chains of hydrogen bonds such as those found in water and proteins are often presumed to be more stable than the sum of the individual H bonds. However, the energetics of cooperativity are complicated by solvent effects and the dynamics of intermolecular interactions, meaning that information on cooperativity typically is derived from theory or indirect structural data. Herein, we present direct measurements of energetic cooperativity in an experimental system in which the geometry and the number of H bonds in a chain were systematically controlled. Strikingly, we found that adding a second H-bond donor to form a chain can almost double the strength of the terminal H bond, while further extensions have little effect. The experimental observations add weight to computations which have suggested that strong, but short-range cooperative effects may occur in H-bond chains.
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