Evidence map›Paper›PMID 28493418›Full record

ArticleJournal of cachexia, sarcopenia and muscle2017

Muscle mass and association to quality of life in non-small cell lung cancer patients.

Asta Bye, Bjørg Sjøblom, Tore Wentzel-Larsen, Bjørn H Grønberg, Vickie E Baracos, Marianne J Hjermstad, Nina Aass, Roy M Bremnes, Øystein Fløtten, Marit Jordhøy

Registry-linked trialOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of cachexia, sarcopenia and muscle, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06255145 (Assessment of Body Composition, Fatigue, Mobility and Functional Status in Post-Stroke Individuals), which is not on this map. Cited by 70 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
70citing papers in PubMed, 4 pooled it
9.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06255145 nacompletednot on this mapstarted 2021, after this paper: background citation

Assessment of Body Composition, Fatigue, Mobility and Functional Status in Post-Stroke Individuals

TypeinterventionalSponsorPamukkale UniversityRan2021 to 2022Enrolled42ConditionsCerebrovascular Stroke, Body CompositionArmsBioelectrical Impedance Analysis
3 · Its place in the literature

Who cites it

70 citing papers in PubMed, 4 syntheses or guidelines pooled it, 147 citations in OpenAlex.

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10 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 10 institutions in 2 countries.

Asta ByeRegional Advisory Unit for Palliative Care, Department of Oncology, Oslo University Hospital, Oslo, Norway.
Bjørg SjøblomDepartment of Internal Medicine, Innlandet Hospital Trust, Hamar, Norway.
Tore Wentzel-LarsenNorwegian Centre for Violence and Traumatic Stress Studies, Oslo, Norway.
Bjørn H GrønbergCancer Clinic, St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway.
Vickie E BaracosDepartment of Oncology, Division of Palliative Care Medicine, University of Alberta, Edmonton, Canada.
Marianne J HjermstadRegional Advisory Unit for Palliative Care, Department of Oncology, Oslo University Hospital, Oslo, Norway.
Nina AassRegional Advisory Unit for Palliative Care, Department of Oncology, Oslo University Hospital, Oslo, Norway.
Roy M BremnesDepartment of Oncology, University Hospital North Norway, Tromsø, Norway.
Øystein FløttenDepartment of Thoracic Medicine, Haukeland University Hospital, Bergen, Norway.
Marit JordhøyDepartment of Internal Medicine, Innlandet Hospital Trust, Hamar, Norway.
Haukeland University Hospital · NOInnlandet Hospital Trust · NONorwegian Centre for Violence and Traumatic Stress Studies · NONorwegian University of Science and Technology · NOOsloMet – Oslo Metropolitan University · NOOslo University Hospital · NOSt Olav's University Hospital · NOUniversity Hospital of North Norway · NOUniversity of Alberta · CAUniversity of Oslo · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCancer wasting is characterized by muscle loss and may contribute to fatigue and poor quality of life (QoL). Our aim was to investigate associations between skeletal muscle index (SMI) and skeletal muscle radiodensity (SMD) and selected QoL outcomes in advanced non-small cell lung cancer (NSCLC) at diagnosis.

methodsBaseline data from patients with stage IIIB/IV NSCLC and performance status 0-2 enrolled in three randomized trials of first-line chemotherapy (n = 1305) were analysed. Associations between SMI (cm

resultsComplete data were available for 734 patients, mean age 65 years. Mean SMI was 47.7 cm

conclusionsLow muscle mass in NSCLC negatively affects the patients' PF, RF, and global QoL, possibly more so in men than in women. However, muscle mass must be below a threshold value before this effect can be detected.

Indexed as

Quality of LifeAgedAged, 80 and overBody CompositionCarcinoma, Non-Small-Cell LungFatigueFemaleHumansLung NeoplasmsMaleMiddle AgedMuscle, SkeletalNeoplasm StagingOrgan SizeWasting SyndromeBody compositionMuscle massNon-small cell lung cancerQuality of life

Identifiers

PMID28493418
PMCPMC5659054
OpenAlexW2612450492

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.