Evidence map›Paper›PMID 28493168›Full record

ArticleTransgenic research2017

Comparative statistical component analysis of transgenic, cyanophycin-producing potatoes in greenhouse and field trials.

Kerstin Schmidt, Jörg Schmidtke, Yvonne Mast, Eva Waldvogel, Wolfgang Wohlleben, Friederike Klemke, Wolfgang Lockau, Tina Hausmann, Maja Hühns, Inge Broer

Abstract read
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In one paragraph

Article in Transgenic research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Cyanophycin Modifications-Widening the Application Potential.Frontiers in bioengineering and biotechnology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 1 country.

Kerstin SchmidtBioMath GmbH, Friedrich-Barnewitz-Str. 8, 18119, Rostock-Warnemünde, Germany. kerstin.schmidt@biomath.de.ORCID 0000-0003-2529-6082
Jörg SchmidtkeBioMath GmbH, Friedrich-Barnewitz-Str. 8, 18119, Rostock-Warnemünde, Germany.
Yvonne MastDepartment of Microbiology/Biotechnology, Interfaculty Institute of Microbiology and Infection Medicine, University of Tübingen, Auf der Morgenstelle 28, 72076, Tübingen, Germany.
Eva WaldvogelDepartment of Microbiology/Biotechnology, Interfaculty Institute of Microbiology and Infection Medicine, University of Tübingen, Auf der Morgenstelle 28, 72076, Tübingen, Germany.
Wolfgang WohllebenDepartment of Microbiology/Biotechnology, Interfaculty Institute of Microbiology and Infection Medicine, University of Tübingen, Auf der Morgenstelle 28, 72076, Tübingen, Germany.
Friederike KlemkeDepartment of Biology, Humboldt-Universität Berlin, Invalidenstr. 110, 10115, Berlin, Germany.
Wolfgang LockauDepartment of Biology, Humboldt-Universität Berlin, Invalidenstr. 110, 10115, Berlin, Germany.
Tina HausmannAgrobiotechnology, Universität Rostock, Justus-von-Liebig-Weg 6, 18059, Rostock, Germany.
Maja HühnsAgrobiotechnology, Universität Rostock, Justus-von-Liebig-Weg 6, 18059, Rostock, Germany.
Inge BroerAgrobiotechnology, Universität Rostock, Justus-von-Liebig-Weg 6, 18059, Rostock, Germany.
Humboldt-Universität zu Berlin · DEInstitute for ImplantTechnology and Biomaterials · DEUniversity of Rostock · DEUniversity of Tübingen · DEForschungszentrum Jülich · DEUniversitätsmedizin Rostock · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Potatoes are a promising system for industrial production of the biopolymer cyanophycin as a second compound in addition to starch. To assess the efficiency in the field, we analysed the stability of the system, specifically its sensitivity to environmental factors. Field and greenhouse trials with transgenic potatoes (two independent events) were carried out for three years. The influence of environmental factors was measured and target compounds in the transgenic plants (cyanophycin, amino acids) were analysed for differences to control plants. Furthermore, non-target parameters (starch content, number, weight and size of tubers) were analysed for equivalence with control plants. The huge amount of data received was handled using modern statistical approaches to model the correlation between influencing environmental factors (year of cultivation, nitrogen fertilization, origin of plants, greenhouse or field cultivation) and key components (starch, amino acids, cyanophycin) and agronomic characteristics. General linear models were used for modelling, and standard effect sizes were applied to compare conventional and genetically modified plants. Altogether, the field trials prove that significant cyanophycin production is possible without reduction of starch content. Non-target compound composition seems to be equivalent under varying environmental conditions. Additionally, a quick test to measure cyanophycin content gives similar results compared to the extensive enzymatic test. This work facilitates the commercial cultivation of cyanophycin potatoes.

Indexed as

Bacterial ProteinsGene Expression Regulation, PlantPlant ProteinsPlants, Genetically ModifiedSolanum tuberosumStarchBacterial ProteinscyanophycinPlant ProteinsStarchComparative assessmentCyanophycinField trialsGenetically modified plantsLinear modelsPotatoStandardized effect sizes

Identifiers

PMID28493168
OpenAlexW2613967464

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.