Evidence map›Paper›PMID 28492788›Full record

ArticleBrazilian journal of cardiovascular surgery

Hemoglobin A1c Levels Predicts Acute Kidney Injury after Coronary Artery Bypass Surgery in Non-Diabetic Patients.

Cevdet Ugur Kocogulları, Atike Tekeli Kunt, Rezan Aksoy, Cagrı Duzyol, Hakan Parlar, Huseyin Saskın, Orhan Fındık

Open access · diamondAbstract read
In one paragraph

Article in Brazilian journal of cardiovascular surgery. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 22 citations in OpenAlex.

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  6. A1C as a Prognosticator of Perioperative Complications of Diabetes: A Narrative Review.Turkish journal of anaesthesiology and reanimation · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Cevdet Ugur KocogullarıSiyami Ersek Training and Research Hospital, Istanbul, Turkey.
Atike Tekeli KuntDerince Training and Research Hospital, Kocaeli, Turkey.
Rezan AksoyKartal Kosuyolu Training and Research Hospital, Istanbul, Turkey.
Cagrı DuzyolDerince Training and Research Hospital, Kocaeli, Turkey.
Hakan ParlarDerince Training and Research Hospital, Kocaeli, Turkey.
Huseyin SaskınDerince Training and Research Hospital, Kocaeli, Turkey.
Orhan FındıkDerince Training and Research Hospital, Kocaeli, Turkey.
Dr. Siyami Ersek Göğüs Kalp Ve Damar Cerrahisi Eğitim Ve Araştırma Hastanesi · TRKartal Koşuyolu High Specialization Training and Research Hospital · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introduction: Elevated hemoglobin A1c levels in patients with diabetes mellitus have been known as a risk factor for acute kidney injury after coronary artery bypass grafting. However, the relationship between hemoglobin A1c levels in non-diabetics and acute kidney injury is under debate. We aimed to investigate the association of preoperative hemoglobin A1c levels with acute kidney injury in non-diabetic patients undergoing isolated coronary artery bypass grafting.

methods: 202 non-diabetic patients with normal renal function (serum creatinine <1.4 mg/dl) who underwent isolated coronary bypass were analyzed. Hemoglobin A1c level was measured at the baseline examination. Patients were separated into two groups according to preoperative Hemoglobin A1c level. Group 1 consisted of patients with preoperative HbA1c levels of < 5.6% and Group 2 consisted of patients with preoperative HbA1c levels of ≥ 5.6%. Acute kidney injury diagnosis was made by comparing baseline and postoperative serum creatinine to determine the presence of predefined significant change based on the Kidney Disease Improving Global Outcomes (KDIGO) definition.

results: Acute kidney injury occurred in 19 (10.5%) patients after surgery. The incidence of acute kidney injury was 3.6% in Group 1 and 16.7% in Group 2. Elevated baseline hemoglobin A1c level was found to be associated with acute kidney injury (P=0.0001). None of the patients became hemodialysis dependent. The cut off value for acute kidney injury in our group of patients was 5.75%.

conclusion: Our findings suggest that, in non-diabetics, elevated preoperative hemoglobin A1c level may be associated with acute kidney injury in patients undergoing coronary artery bypass grafting. Prospective randomized studies in larger groups are needed to confirm these results.

Indexed as

Acute Kidney InjuryAdultAgedAged, 80 and overBiomarkersCoronary Artery BypassCreatinineFemaleGlycated HemoglobinHumansIncidenceMaleMiddle AgedPostoperative ComplicationsPredictive Value of TestsRetrospective StudiesBiomarkersCreatinineGlycated Hemoglobinhemoglobin A1c protein, human

Identifiers

PMID28492788
PMCPMC5409247
OpenAlexW2605310692

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.