Evidence map›Paper›PMID 28492721›Full record

ArticleClinics (Sao Paulo, Brazil)2017

Treatment of acromegaly patients at the Federal University of Triângulo Mineiro (UFTM): Experience Report.

Maria de Fátima Borges, Beatriz Hallal Jorge Lara, Janaíne Machado Tomé, Leopoldo Prezia de Araújo, Flávio Cesar Lucas Bugiga, Júlio Cláudio Sousa, Jacqueline Mendes Fonseca Soares, Roberto Alexandre Dezena, Beatriz Pires Ferreira

Open access · goldAbstract read
In one paragraph

Article in Clinics (Sao Paulo, Brazil), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Maria de Fátima BorgesDivisão de Endocrinologia e Metabolismo, Universidade Federal do Triângulo Mineiro, Uberaba, MG, BR.
Beatriz Hallal Jorge LaraDivisão de Endocrinologia e Metabolismo, Universidade Federal do Triângulo Mineiro, Uberaba, MG, BR.
Janaíne Machado ToméDivisão de Endocrinologia e Metabolismo, Universidade Federal do Triângulo Mineiro, Uberaba, MG, BR.
Leopoldo Prezia de AraújoDivisão de Neurocirurgia, Universidade Federal do Triângulo Mineiro, Uberaba, MG, BR.
Flávio Cesar Lucas BugigaDivisão de Endocrinologia e Metabolismo, Universidade Federal do Triângulo Mineiro, Uberaba, MG, BR.
Júlio Cláudio SousaDivisão de Otorrinolaringologia, Universidade Federal do Triângulo Mineiro, Uberaba, MG, BR.
Jacqueline Mendes Fonseca SoaresDivisão de Endocrinologia e Metabolismo, Universidade Federal do Triângulo Mineiro, Uberaba, MG, BR.
Roberto Alexandre DezenaDivisão de Neurocirurgia, Universidade Federal do Triângulo Mineiro, Uberaba, MG, BR.
Beatriz Pires FerreiraDivisão de Endocrinologia e Metabolismo, Universidade Federal do Triângulo Mineiro, Uberaba, MG, BR.
Universidade Federal do Triângulo Mineiro · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objective: To evaluate the effectiveness of the treatment of acromegaly patients at the Federal University of Triangulo Mineiro.

methods: Cross-sectional and retrospective study of thirty cases treated over a period of two decades.

results: 17 men (56.7%) aged 14-67 years and 13 women aged 14-86 years were analyzed. Twenty-one patients underwent transphenoidal surgery, whichwas associated with somatostatin receptor ligands in 11 patients (39.3%), somatostatin receptor ligands + radiotherapyin 5 patients (17.8%), radiotherapy in 3 patients (10.7%), and radiotherapy + somatostatin receptorligands + cabergoline in 1 patient (3.6%). Additionally, 2 patients underwent radiotherapy and surgeryalone. Six patients received somatostatin receptor ligands before surgery, and 2 were not treated due to refusal and death. Nine patients have died, and 20 are being followed; 13 (65%) have growth hormonelevels o1 ng/mL, and 11 have normal insulin-like growth factor 1 levels.

conclusion: The current treatment options enable patients seen in regional reference centers to achieve strict control parameters, which allows them to be treated close to their homes.

Indexed as

AcromegalyAdenomaAdolescentAdultAgedAged, 80 and overBlood GlucoseBrazilCombined Modality TherapyCross-Sectional StudiesFemaleGigantismGrowth HormoneGrowth Hormone-Secreting Pituitary AdenomaHumansInsulin-Like Growth Factor IBlood GlucoseGrowth HormoneInsulin-Like Growth Factor ILigandsReceptors, Somatostatin

Identifiers

PMID28492721
PMCPMC5401613
OpenAlexW2614057869

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.