ReviewInternational journal of environmental research and public health2017
Nasal Irrigation: An Imprecisely Defined Medical Procedure.
Review in International journal of environmental research and public health, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 32 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Efficacy and Safety of Healsea® Hypertonic Nasal Spray 2.7% in the Treatment of Acute Infectious Rhinitis in Adults
Efficacy and Safety of Healsea® Babykids in the Treatment of Acute Infectious Rhinitis Symptoms in Children
Who cites it
32 citing papers in PubMed, 2 syntheses or guidelines pooled it, 95 citations in OpenAlex.
- The Statistical Fragility of Saline Nasal Irrigation for Rhinosinusitis: A Systematic Review.The Laryngoscope · 2026Pooled it
- Clinical Practice Guideline: Nasal Irrigation for Chronic Rhinosinusitis in Adults.Clinical and experimental otorhinolaryngology · 2022Guideline
- Prospective, randomized, controlled, open-label study to compare efficacy of a mineral-rich solution vs normal saline after complete ethmoidectomy.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2019Trial
- Nasal Irrigation in Children: From Pathophysiological Rationale to Clinical Practice.Children (Basel, Switzerland) · 2026Review
- Article
- Incidence and Risk Factors of Postoperative Meningitis Following Endoscopic Endonasal Transsphenoidal Surgery: A Study in Thailand.Asian journal of neurosurgery · 2025Article
- Nasal Irrigations: A 360-Degree View in Clinical Practice.Medicina (Kaunas, Lithuania) · 2025Review
- Efficacy, Safety, and Tolerability of Nasal Wash in Patients with Upper Respiratory Tract Diseases.International archives of otorhinolaryngology · 2025Article
- Protocol for a Multicenter, Double-Blind, Randomized Controlled Trial on Jal Neti: Current Trends, Standardization of Process, and Clinical Efficacy.Journal of pharmacy & bioallied sciences · 2025Article
- Efficacy of hypertonic nasal spray with algae in rhinosinusitis.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025Observational
- Association of Childhood IgA Vasculitis With Allergic Rhinitis and Chronic Rhinosinusitis.Kidney international reports · 2024Article
- A Comprehensive Review Exploring Allergic Rhinitis With Nasal Polyps: Mechanisms, Management, and Emerging Therapies.Cureus · 2024Review
- Enabling methanol fixation of pediatric nasal wash during respiratory illness for single cell sequencing in comparison with fresh samples.Pediatric research · 2024Article
- A pilot study investigating the effects of a manuka honey sinus rinse compared to a standard sinus rinse on sino-nasal outcome test scores in cystic fibrosis patients.Pilot and feasibility studies · 2022Article
- The Role of Seawater and Saline Solutions in Treatment of Upper Respiratory Conditions.Marine drugs · 2022Review
- Article
- Nasal saline irrigation: prescribing habits and attitudes of physicians and pharmacists.Scandinavian journal of primary health care · 2021Article
- Current Perspective on Nasal Delivery Systems for Chronic Rhinosinusitis.Pharmaceutics · 2021Review
- Review of the use of nasal and oral antiseptics during a global pandemic.Future microbiology · 2021Review
- A multicenter survey on the effectiveness of nasal irrigation devices in rhinosinusitis patients.Laryngoscope investigative otolaryngology · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Nasal irrigation (NI) is an old practice of upper respiratory tract care that likely originated in the Ayurvedic medical tradition. It is used alone or in association with other therapies in several conditions-including chronic rhinosinusitis and allergic rhinitis-and to treat and prevent upper respiratory tract infections, especially in children. However, despite it being largely prescribed in everyday clinical practice, NI is not included or is only briefly mentioned by experts in the guidelines for treatment of upper respiratory tract diseases. In this review, present knowledge about NI and its relevance in clinical practice is discussed to assist physicians in understanding the available evidence and the potential use of this medical intervention. Analysis of the literature showed that NI seems to be effective in the treatment of several acute and chronic sinonasal conditions. However, although in recent years several new studies have been performed, most of the studies that have evaluated NI have relevant methodologic problems. Only multicenter studies enrolling a great number of subjects can solve the problem of the real relevance of NI, and these studies are urgently needed. Methods for performing NI have to be standardized to determine which solutions, devices and durations of treatment are adequate to obtain favorable results. This seems particularly important for children that suffer a great number of sinonasal problems and might benefit significantly from an inexpensive and simple preventive and therapeutic measure such as NI.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.