Evidence map›Paper›PMID 28492063›Full record

ArticleJournal of nature and science2017

Vaccination with Killed but Metabolically Active

Pei-Feng Liu, Yanhan Wang, Yu-Tsueng Liu, Chun-Ming Huang

Open access · greenAbstract read
In one paragraph

Article in Journal of nature and science, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 98% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Pei-Feng LiuDepartment of Dermatology, University of California, San Diego, San Diego, USA.
Yanhan WangDepartment of Dermatology, University of California, San Diego, San Diego, USA.
Yu-Tsueng LiuDivision of Infectious Diseases, Department of Medicine, University of California, San Diego, USA.
Chun-Ming HuangDepartment of Dermatology, University of California, San Diego, San Diego, USA.
University of California, San Diego · US

Funding

Immunological Secretomes of the Early Anthrax InfectionR01AI067395 · NIAID · VETERANS MEDICAL RESEARCH FDN/SAN DIEGO · PI HUANG, CHUN-MING · 2006 to 2010
$1.2M
Indigenous Free Fatty Oleic acid Against MRSA Skin InfectionR21AI088147 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI HUANG, CHUN-MING · 2010 to 2011
$460k
Acne Vaccines Targeting a Surface Sialidase and a Secreted CAMP Factor ToxinR41AR056169 · NIAMS · VAXIN INC. · PI HUANG, CHUN-MING · 2008 to 2008
$100k
NIAID NIH HHS R01 AI067395NIAID NIH HHS R21 AI088147NIAMS NIH HHS R41 AR056169
6 · The paper itself

Abstract

There is a need for a fast and simple method for vaccine production to keep up with the pace of a rapidly spreading virus in the early phases of the influenza pandemic. The use of whole viruses produced in chicken eggs or recombinant antigens purified from various expression systems has presented considerable challenges, especially with lengthy processing times. Here, we use the killed but metabolically active (KBMA)

Indexed as

H1N1 swine origin influenza A virusHemagglutininIntranasal vaccineKBMAmicrobe based-vaccine

Identifiers

PMID28492063
PMCPMC5421401
OpenAlexW2589291865

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.